December 14, 2009
CURRICULUM VITAE
NAME: George R. Jackson, M.D., Ph.D.
PRESENT POSITION AND ADDRESS:
Professor
Departments of Neurology and Neuroscience and Cell Biology
Director, Mitchell Center for Neurodegenerative Diseases
John Sealy Chair for Parkinson’s Disease
The University of Texas Medical Branch
301 University Blvd., MRB 10.138
Galveston, TX 77555-1045
Phone (409) 747-0017
Fax (409) 747-0015
e-mail grjackso@utmb.edu
BIOGRAPHICAL:
Born March 25, 1962 in Midland, Texas
U.S. Citizen
EDUCATION:
8/80-5/84: Bachelor of Science with Honors, University of Texas at Austin, Austin, TX. Major: Nutrition
5/84-8/86: Master of Arts, University of Texas at Austin, Austin, TX. Major: Nutrition. Minor: Biochemistry
8/86-5/93: Doctor of Philosophy, University of Texas Medical Branch at Galveston, Galveston, TX. Major: Human Genetics and Cell Biology
8/86-5/93: Doctor of Medicine, University of Texas Medical Branch at Galveston, Galveston, TX
POSTGRADUATE TRAINING:
1993-1994: Intern, Department of Medicine, University of California, Los Angeles School of Medicine, Los Angeles, CA
1994-1997: Resident, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA
1997-1999: fellow, Neurogenetics, Howard Hughes Medical Institute (supervisor, S. Lawrence Zipursky, Ph.D.), and Movement Disorders, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA (supervisor Jeff Bronstein, M.D., Ph.D.)
BOARD CERTIFICATION: Neurology (1/1999-1/2009; recert. exam scheduled 3/24/09)
LICENSURE INFORMATION: CA A53511 TX FTL 42746
PROFESSIONAL AND TEACHING EXPERIENCE:
1999-2006: Assistant Professor in Residence, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA
7/06-8/08: Associate Professor in Residence, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA
1/07-8/08: Senior scientist, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA
9/08-present: Professor, Departments of Neurology, Neuroscience and Cell Biology, and Biochemistry and Molecular Biology, University of Texas medical Branch at Galveston, Galveston, TX
1/09-present: Director, George P. and Cynthia Woods Mitchell Center for Neurodegenerative Diseases
RESEARCH ACTIVITIES:
Area of Research
Molecular and cellular basis of neurodegenerative disorders; application of functional genomics to analysis of human neuropsychiatric disorders
Grant support
Current
American Health Assistance Foundation
Validation and Characterization of Tau Modifiers In Vivo
PI Jackson; 5%; $129,000 annual 4/1/2007-3/31/2010
R01 ES015747 NIH/NIEHS (at UCLA)
Environmental Toxin Interactions with Genetic Risks for Parkinson's Disease
PI Krantz, D.E.; 5%; $47,000 annual 8/1/07 – 5/31/11
P01 ES016732 NIH/NIEHS
Center for Gene Environment in Parkinson's Disease
Pesticide Mechanisms and PD: Genetic Studies in Drosophila
PI: Chesselet, M.-F.; 10%; $100,000 annual 7/1/2008-6/30/2013
Subproject: Pesticide Mechanisms and PD: Genetic Studies in Drosophila
R01 FD003359 FDA
Creatine Therapy to Treat Huntington’s Disease: A Phase 3 Study
PI: Hersch, S.M. 7/10/2017-6/30/2011. Role: Site PI
U01NS052592
Coenzyme Q in Huntington’s Disease
PI: Cudkowicz, M.E. 9/30/2005-11/30/2010. Role: Site PI
R01 HD051844 NICHHD
Gait and Step Training to Prevent Falls in Parkinson’s Disease
PI: Protas, E.J. 9/25/2006-6/30/2012. Role: Collaborator
Past
R01 NS046489 NIH/NINDS/NIA
Molecular Genetics of Tau-Associated Neurodegeneration
PI Jackson; 40%; $250,000 annual 7/15/04-7/14/08 (no cost extension through 6/30/09)
P50 AG16570 NIH/NIA
UCLA Alzheimer's Disease Research Center
PI Cummings, J.L.; 40%; $125,000 annual 4/1/04-8/31/08
Subproject: “Screening for Drugs in a Transgenic Drosophila Model”
K08 NS002116 NIH/NINDS
Molecular Genetics of Polyglutamine-Induced Degeneration
PI Jackson; 85%; $152,255 annual 8/99-8/04
R01 HG02449 NIH/NHGRI/NINDS
Prospective Huntington at Risk Observational Study (PHAROS)
PI: Shoulson, I.; 5%; $22,950 annual 07/01/02-06/30/07
Hereditary Disease Foundation/ John Wasmuth Memorial Postdoctoral Fellowship (Sang)
p47 and p97 as Potential Modifiers of HD
PI: Sang, T.-K. effort as mentor only; $41,441 annual 2/01/03-1/31/05
American Parkinson’s Disease Association
Mutant Parkin-Induced Dopaminergic Neurodegeneration in Drosophila
PI: Jackson; 5%; $50,000 9/01/04-8/31/05
To use a Drosophila model to elucidate mechanisms of mutant parkin-induced neurodegeneration
Parkinson’s Disease Foundation
A Model to Study Neurodegeneration Caused By Human Parkin Mutations
PI: Jackson; $40,000 7/01/06-6/30.07
To use a Drosophila model to elucidate mechanisms whereby parkin mutations give rise to neurodegeneration.
COMMITTEE RESPONSIBILITIES:
International
None
National
NIH Neurodegeneration and Biology of Glia study section, 2005 – 2007; ad hoc member,
NIH Cellular and Molecular Biology of Neurodegeneration study section, 2007-present; regular member
NIH Drug Discovery special emphasis panel, 2006-present, ad hoc reviewer
American Federation for Aging Research
State/Regional
State of California Department of Health Services Alzheimer’s Disease Program
UTMB
Chair, Mouse Neurogenetics Search Committee
Drosophila Genetics Search Committee
Medical Service, Research and Development (MSRDP) Plan Board of Directors
School
Departmental
Neuroscience Graduate Program Advisory Committee
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