December 14, 2009 CURRICULUM VITAE
NAME: George R. Jackson, M.D., Ph.D.
PRESENT POSITION AND ADDRESS: Professor Departments of Neurology and Neuroscience and Cell Biology Director, Mitchell Center for Neurodegenerative Diseases John Sealy Chair for Parkinson’s Disease The University of Texas Medical Branch 301 University Blvd., MRB 10.138 Galveston, TX 77555-1045 Phone (409) 747-0017 Fax (409) 747-0015 e-mail grjackso@utmb.edu
BIOGRAPHICAL: Born March 25, 1962 in Midland, Texas U.S. Citizen
EDUCATION:
8/80-5/84: Bachelor of Science with Honors, University of Texas at Austin, Austin, TX. Major: Nutrition
5/84-8/86: Master of Arts, University of Texas at Austin, Austin, TX. Major: Nutrition. Minor: Biochemistry
8/86-5/93: Doctor of Philosophy, University of Texas Medical Branch at Galveston, Galveston, TX. Major: Human Genetics and Cell Biology
8/86-5/93: Doctor of Medicine, University of Texas Medical Branch at Galveston, Galveston, TX
POSTGRADUATE TRAINING:
1993-1994: Intern, Department of Medicine, University of California, Los Angeles School of Medicine, Los Angeles, CA
1994-1997: Resident, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA
1997-1999: fellow, Neurogenetics, Howard Hughes Medical Institute (supervisor, S. Lawrence Zipursky, Ph.D.), and Movement Disorders, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA (supervisor Jeff Bronstein, M.D., Ph.D.)
BOARD CERTIFICATION: Neurology (1/1999-1/2009; recert. exam scheduled 3/24/09)
LICENSURE INFORMATION: CA A53511 TX FTL 42746
PROFESSIONAL AND TEACHING EXPERIENCE:
1999-2006: Assistant Professor in Residence, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, CA
7/06-8/08: Associate Professor in Residence, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA
1/07-8/08: Senior scientist, Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, CA
9/08-present: Professor, Departments of Neurology, Neuroscience and Cell Biology, and Biochemistry and Molecular Biology, University of Texas medical Branch at Galveston, Galveston, TX
1/09-present: Director, George P. and Cynthia Woods Mitchell Center for Neurodegenerative Diseases
RESEARCH ACTIVITIES:
Area of Research
Molecular and cellular basis of neurodegenerative disorders; application of functional genomics to analysis of human neuropsychiatric disorders
Grant support
Current
American Health Assistance Foundation Validation and Characterization of Tau Modifiers In Vivo PI Jackson; 5%; $129,000 annual 4/1/2007-3/31/2010
R01 ES015747 NIH/NIEHS (at UCLA) Environmental Toxin Interactions with Genetic Risks for Parkinson's Disease PI Krantz, D.E.; 5%; $47,000 annual 8/1/07 – 5/31/11
P01 ES016732 NIH/NIEHS Center for Gene Environment in Parkinson's Disease Pesticide Mechanisms and PD: Genetic Studies in Drosophila PI: Chesselet, M.-F.; 10%; $100,000 annual 7/1/2008-6/30/2013 Subproject: Pesticide Mechanisms and PD: Genetic Studies in Drosophila
R01 FD003359 FDA Creatine Therapy to Treat Huntington’s Disease: A Phase 3 Study PI: Hersch, S.M. 7/10/2017-6/30/2011. Role: Site PI
U01NS052592 Coenzyme Q in Huntington’s Disease PI: Cudkowicz, M.E. 9/30/2005-11/30/2010. Role: Site PI
R01 HD051844 NICHHD Gait and Step Training to Prevent Falls in Parkinson’s Disease PI: Protas, E.J. 9/25/2006-6/30/2012. Role: Collaborator
Past
R01 NS046489 NIH/NINDS/NIA Molecular Genetics of Tau-Associated Neurodegeneration PI Jackson; 40%; $250,000 annual 7/15/04-7/14/08 (no cost extension through 6/30/09)
P50 AG16570 NIH/NIA UCLA Alzheimer's Disease Research Center PI Cummings, J.L.; 40%; $125,000 annual 4/1/04-8/31/08 Subproject: “Screening for Drugs in a Transgenic Drosophila Model”
K08 NS002116 NIH/NINDS Molecular Genetics of Polyglutamine-Induced Degeneration PI Jackson; 85%; $152,255 annual 8/99-8/04
R01 HG02449 NIH/NHGRI/NINDS Prospective Huntington at Risk Observational Study (PHAROS) PI: Shoulson, I.; 5%; $22,950 annual 07/01/02-06/30/07
Hereditary Disease Foundation/ John Wasmuth Memorial Postdoctoral Fellowship (Sang) p47 and p97 as Potential Modifiers of HD PI: Sang, T.-K. effort as mentor only; $41,441 annual 2/01/03-1/31/05
American Parkinson’s Disease Association Mutant Parkin-Induced Dopaminergic Neurodegeneration in Drosophila PI: Jackson; 5%; $50,000 9/01/04-8/31/05 To use a Drosophila model to elucidate mechanisms of mutant parkin-induced neurodegeneration
Parkinson’s Disease Foundation A Model to Study Neurodegeneration Caused By Human Parkin Mutations PI: Jackson; $40,000 7/01/06-6/30.07 To use a Drosophila model to elucidate mechanisms whereby parkin mutations give rise to neurodegeneration.
COMMITTEE RESPONSIBILITIES:
International
None
National
NIH Neurodegeneration and Biology of Glia study section, 2005 – 2007; ad hoc member, NIH Cellular and Molecular Biology of Neurodegeneration study section, 2007-present; regular member NIH Drug Discovery special emphasis panel, 2006-present, ad hoc reviewer
American Federation for Aging Research
State/Regional
State of California Department of Health Services Alzheimer’s Disease Program
UTMB
Chair, Mouse Neurogenetics Search Committee Drosophila Genetics Search Committee Medical Service, Research and Development (MSRDP) Plan Board of Directors
School
Departmental
Neuroscience Graduate Program Advisory Committee
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