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UNIVERSITY OF WARWICK
Proposal Form for New or Revised Modules (MA1- version 3)
For consideration by the Undergraduate Studies Committee/Sub-Faculty or Graduate Studies Committee only.
NB: 1. If it is unclear whether or not a change to an existing module should be proposed on this form, the Chair or Secretary of the Undergraduate Studies Committee/Sub-Faculty or Graduate Studies Committee should be consulted.
2. In order to reduce printing costs please delete the text provided as guidance in the body of the form before submission to the Faculty Secretariat. However, all sections must be completed to the satisfaction of the Faculty Undergraduate/Graduate Studies Committee.
1. Title of Module:
CH269 Introduction to Biological and Medicinal Chemistry
2. New or Revised Module:
New module? [ X]
Revised module? [ ]
Level: D (Doctorate) [ ]
M (Masters) [ ]
H (Honours) [X ]
I (Intermediate) [ ]
C (Certificate) [ ]
If this new module replaces an existing approved module specify the code and title of the module to be discontinued and date on which change will occur:
Replaces CH2A3 Introduction to Biological Chemistry and CH2A2 Introduction to Medicinal Chemistry, October 2009
If this is a proposal for a revised module, specify which sections have been amended, and give an outline rationale for the changes:
3. Date of Introduction of new module or revised version of existing module:
4. Department Responsible for Teaching:
If the module is taught by more than one department please indicate this (for matrix purposes):
Name of Module Leader:
Prof Tim Bugg
If the module leader is not a member of Warwick staff and has not previously been appointed as a module leader/tutor, please include a C.V with this form.
5. Availability/Location of module within courses:
List the degree courses on which this module is available, indicating the year of study, whether the module is core or an option and the credit weighting in each case. Include any part-time or 2+2 degrees on which this module is available.
*Credit should be in one of the following tariffs:
6, 12, 18, 24, 48 credits; or
7.5, 15, 30, 45, 60 credits; or
(for postgraduate courses only) 10, 20, 30, 40, 50,60 credits
6. Consultation with other Departments:
It is important that any departments affected by the introduction of this module are consulted before the module is considered by the relevant Faculty committee.
Which other departments will be affected by the introduction/revision of this module (i.e. other departments offering the module as an option in their degree courses, including joint degree courses involving the department proposing the module)? Please give details of any consultations undertaken and indicate whether the other departments have approved the proposal.
Describe the relationship to any other modules with which the new module has a close connection and any prerequisite relationships.
This module follows on from new introductory biological chemistry material in the revised 1st year Chemistry course, and leads on to biological chemistry modules CH3D2 and CH3D3 in Year 3.
8. Module Aims:
These should identify the module’s broad educational purposes. Indicate how the module will contribute to the achievement of the aims of the degree courses on which it is available.
This is a core module for all Chemistry students, introducing the principles of biological chemistry, which is an important facet of a modern Chemistry degree, and is an active topic of research in the Chemistry Department at Warwick. The module covers three major topics in biological chemistry: carbohydrate chemistry; enzymes & enzyme catalysis; and an introduction to medicinal chemistry & drug discovery. The module is particularly relevant to BSc Biomedical Chemistry and MChem Chemical Biology joint degree students, and BSc/MChem Chemistry with Medicinal Chemistry students. This module is a prerequisite for the subsequent optional modules CH3D2 Enzymes and Natural product biosynthesis and CH408 Advanced Medicinal Chemistry.
A-level biology is not an essential prerequisite for the module, but students who do not have this qualification will find they have met little of the material before. Many of the concepts in this module build on concepts assimilated in the core module for all students Organic Chemistry II (Mech and Sterochemistry part). Consequently this module should ideally be delivered after this one.
9. Learning Outcomes:
Successful completion of the module leads to the learning outcomes. The learning outcomes identify the knowledge, skills and attributes developed by the module. Learning Outcomes should be presented in the following format using the table below:
By the end of the module students should be able to...
Learning Outcomes should include reference to subject knowledge and understanding, key skills, cognitive skills and subject-specific practical and professional skills and be clearly relevant to fulfilling the educational aims. Learning Outcomes should be measurable by the assessment methods for the module. Indicate how the module will contribute to the achievement of degree course learning objectives.
(a) Subject knowledge and understanding
The knowledge and understanding that a student will be expected to have upon completion, such as : ‘a theoretical knowledge of the principles and methods of archaeology’ or ‘a knowledge of the major types of chemical reaction and the main characteristics associated with them.’
(b) Key Skills
Communication (written, verbal, graphical...)
Use of information technology (e.g. WP, www, databases, spreadsheets, specialist packages)
Ability to learn
Others (e.g. teamwork)
(c) Cognitive Skills
For example: ability in critical analysis; the ability to formulate and test concepts and hypotheses.
(d) Subject-Specific/Professional Skills
For example: laboratory skills; scientific support writing; research skills and methods.
Give an outline of the syllabus for the module.
Carbohydrates. Cellular energy and glucose; the structure of D-glucose, anomers and the anomeric effect; the structures and functions of monosaccharides; the glycosidic bond; oligosaccharides – structures and functions of disaccharides and polysaccharides; biosynthesis of oligosaccharides (5 lectures)
Proteins & Enzymes. Protein structure, information flow from DNA to RNA to proteins; Enzyme catalysis, transition state theory, Michaelis-Menten kinetics, selected examples of enzyme catalytic mechanisms; use of enzymes for biocatalysis, resolution of enantiomers (5 lectures)
Introduction to Medicinal Chemistry. Introduction to drug discovery process; enzyme inhibition, examples of enzyme inhibitors; receptors, introduction, structure/function of receptors; selected examples of receptor agonists/antagonists (5 lectures)
11. Illustrative Bibliography:
List the core texts only. The illustrative bibliography should provide an indication of the focus and level of the reading required by this module, rather than the full range (this should not be more than half a page):
“Organic Chemistry”, J. Clayden, N. Greeves, S. Warren & P. Wothers, OUP, 2001 (core text for all Organic Chemistry modules)
“Introduction to Enzyme and Coenzyme Chemistry”, T.D.H. Bugg, 2nd edition, Blackwells Science, 2004
“An Introduction to Medicinal Chemistry”, G.L. Patrick, 3rd edition, OUP, 2005
“Biochemistry”, L. Stryer, 5th edition, W.H. Freeman and Company, New York, 2001
Give the number of each type of teaching event per week and the length of each session in hours.
13. Assessment Methods:
Are any resources required for this module which are not already available from the Department’s own baseline resources (e.g. staff costs, accommodation, equipment, minor works, library costs, audio visual and computing facilities, vacation study requirements)? Is the module likely to require high usage of centrally timetabled teaching rooms or specific slots (e.g. for a module on a part time postgraduate course)?
Any additional requirements should be discussed with the appropriate Officer (see list below) before submitting the proposal.
List any additional requirements and indicate the outcome of any discussions.
Signature of Module Leader:
Signature of Chair of Department:
Assessment Details (information required by the Exams Office)
This form should be completed only for modules to be assessed by an exam organised by the Exams Office
The form does not have to be submitted for approval but should be sent to Andrea Humber in the Exams Office. If this information is not provided the module cannot be set up on the Student Record System and students will therefore be unable to register for the module and exam. If you have any queries about this form please contact Andrea Humber in the Examination Office (ext 74160)
Indicate all available methods of assessment in the table below
Will this module be examined together with any other module (sectioned paper)? If so please give details.
Is the module to be examined by 1 paper [ x ]
or 2 papers [ ]
When will the exam take place (e.g. Jan, April, Summer)? . Summer . . . . . . .
Is reading time required? Yes [ ] No [ x ]
Give any special exam timetable arrangements
List any other special stationery requirements (e.g. Data books, tables etc):
Type of Paper
Seen: Yes [ ] No [ x ]
Open Book : Yes [ ] No [ x ]
Restricted: Yes [ ] No [ x ]
Where restricted please provide list of texts permitted here:
|NB: If it is unclear whether or not a change to an existing module should be proposed on this form, the Chair or Secretary of the Undergraduate Studies Committee/Sub-Faculty or Graduate Studies Committee should be consulted. In order to reduce printing costs please||Description according to the Faculty of Graduate and Postdoctoral Studies|
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