College of veterinary medicine north carolina state university m. Christine McGahan, Professor and Department Head




НазваниеCollege of veterinary medicine north carolina state university m. Christine McGahan, Professor and Department Head
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ANNUAL REPORT


2008-2009


DEPARTMENT OF MOLECULAR BIOMEDICAL SCIENCES


COLLEGE OF VETERINARY MEDICINE



NORTH CAROLINA STATE UNIVERSITY


M. Christine McGahan, Professor and Department Head




Prepared May 2009




Table of Contents


Page
















Departmental Report

3

I.

Changes in Environment

3

II.

Compact Plan

3

III.

Diversity

3

IV.

Instructional Program

9

V.

Faculty

17

VI.

Students

18

VII.

Research

19

VIII.

Administration and Staff

19

IX.

Recommendations and concerns for the future

20

X.

The University’s Five Focus Areas

23

Appendix I

List of Faculty/EPA Employees Including Graduate Students

27

Appendix II

List of Administrative and Staff Personnel

28

Appendix III

Courses Offered by Departmental Faculty Including DVM courses

Presented by Departmental Faculty and Graduate Courses Offered by and Participated in by Departmental Faculty

31

Appendix IV

Clinical Service Offered by Departmental Faculty

33

Appendix V

Publications, Presentations, Intellectual Property by Departmental Faculty

61

Appendix VI

Professional Activities by Departmental Faculty (Includes Memberships on Research Grant and Study Reviews, Memberships on Editorial Boards, and Ad hoc Manuscript Reviews, Committee Memberships within MBS, CVM, NCSU, and National Committees

73

Appendix VII

Research Grants Awarded to Departmental Faculty

I. Change in Environment

Faculty retirement: N/A


Faculty resignations:

Linda Martin; Assistant Professor of Cell Biology; July 1, 2008

Anthony Pease; Assistant Professor of Radiology; September 2, 2008

Doodipala Reddy; Assistant Professor of Neuroscience and Pharmacology; July 2, 2008


Faculty hires:

Gabriela Seiler; Associate Professor of Radiology; appointment begins July 1, 2009.


We currently have one faculty position open for identified needs in Pharmacology. We are unsure about whether we will be allowed to recruit for this position because of the current budget situation. We have already lost the Stem Cell position that we had begun recruitment for last year.


We are anticipating serious budget cuts at the State level which will negatively impact the department. At this point in time we do not know how much of our budget is in jeopardy. This will be a major challenge for the Department and College moving forward.


II. Compact Plan: For 2008-2010 the Compact Plan was developed at the College level.


III. Diversity


Kenneth Adler has been awarded a supplement to his NIH grant for “underrepresented minorities” for Ms. Teresa Green, a graduate student in his laboratory.


Prema Arasu, within context of diversity strategies as defined by NCSU Office of Diversity, (http://www.ncsu.edu/odi/initiatives/Diversity_Advisory.pdf), has: helped coordinate outreach seminars focused on livestock production/biofuels/health with NCSU faculty and students and external stakeholders (through USDA funded award; teamed with CVM Faculty Maria Correa and Isabel Gimeno and CALS faculty Vivek Fellner and Ratna Sharma); served as advisor for newly formed “Minority Association for Pre-Medical Students” Fall 2008; in the process, Dr. Arasu consulted with Dr. Anita Flick and we agreed that this group of students was better served by coming under the umbrella of the NCSU Pre-Health Club. From this experience, Dr. Arasu was also able to help College of Humanities and Social Sciences via Dean Jeff Braden to link with the Pre-Health Club and establish a new chapter for students interested in careers related to mental health (Dr. Arasu served only in facilitating role); served as advisor and coordinator for two undergraduate students interested in international health experiences - one worked with Public Health Foundation of India in New Delhi, India over the summer 2008; contributed to article on CVM women in science and health for regional news magazine, Women’s Edge; completed term (07/08) as advisor to university Graduate Student Association; served as NCSU representative to Research Triangle Global Coordinating Council (organized by RTRP Doug Aitkin/Ted Abernathy); serving on NCSU College of Management Biosciences Management/Industry (external) Advisory Board; connected NCSU CVM as a partner with the national Alliance for Oral Contraception of Cats and Dogs, and with the Global Alliance for Rabies Control.


Jill Barnes has contributed to improving diversity: Member, Ad-Hoc Diversity Committee (NCSU CVM); Attended “Advising students of color” workshop April 19; USDA, Veterinary Career Pathways Program, May 2008, mentored six minority students in the program in veterinary anatomy “short course”, consisted of 5 weeks of 7 hrs of instruction/week on the limbs/ thoracic cavity /head /abdominal cavity; SAVE program, NC A&T students, heart dissection lab; won the NCSU Faculty Diversity Award, 2009.


Gregg Dean participated in DVM admissions, molecular biology training program, DVM/PhD training program, and GAANN program. Recruited and hired undergraduate minority student, objective is to provide mentorship prior to application to DVM program and participated in ‘Advising students of color’’ workshop April 2008.


Troy Ghashghaei has hired and advised students, postdocs, and technicians from multiple ethnic backgrounds: Raul Salinas-Mordagon (Technician; Hispanic), Benjamin Jacquet (Ph.D. Student; Belgian), Jihey Lim (Postdoc; Korean), Atif Sheikh (undergraduate; Pakistani background), and Huixuan Liang (Ph.D student; Chinese). He also has an equal distribution of male-to-female ratio in the laboratory.


Jorge Piedrahita is a Co-PI in an NIH training grant to bring minority undergraduate and graduates into sciences (PI - Trudy McKay). Program is Initiative for Maximizing Student Diversity (IMSD; http://www.ncsu.edu/grad/imsd/index.php). He is a member of the steering committee and of the admission committee for this program. Dr. Piedrahita participated as a panel member for the BFF (Building Future Faculty) program.


Barbara Sherry serves on the Executive Committee for Expanding Your Horizons Workshops, Spring 2009. NCSU invites 400 seventh grade girls, with an emphasis on those from under-represented groups, to participate in a single-day conference to encourage their pursuit of scientific careers. Dr. Sherry organized participation of 60 -100 of the girls at the College of Veterinary Medicine, for workshops developed by colleagues. We scheduled a record 9 workshops at the College of Veterinary Medicine for March 3rd 2009, but unfortunately the conference was cancelled the day before due to snow!


IV. Instructional Program Initiatives including curriculum development and program review


Curriculum Development

MBS faculty are actively involved in the ongoing curricular review and revision. Efforts have been made by faculty to develop and introduce teaching innovations to enhance student problem-solving and communication abilities. This is particularly evident in the selective courses taught at the end of each semester, which provide a variety of offerings, which expand flexibility in the curriculum and new and varied experiences for students.


We are continuing to work on changes within existing courses to incorporate molecular medicine into the curriculum. We are continuing to work on the Physiology course (VMA 913 and 923) to include genomics and molecular medicine concepts, as well as to better align the subject matter in order to match more closely with Anatomy.


Prema Arasu participated in CVM sub-committee (FCCCE, Subgroup Core led by Dr. Jennifer Neel) on CVM core curriculum reform/assessment. She formed working group to develop a public heatlh focus/courses/track at the undergraduate level at NCSU; applied for sponsorship and was awarded paid slot to attend the July 2008 AACU “The Educated Citizen and Public health” workshop in Crystal City, Virgina/DC (helped obtain matching support from Provost's office and attended workshop together with Dr. Maria Correa, CVM; Gerry Luginbuhl, CALS; Maxine Thompson, CHASS). Our efforts have culminated in the development of the first course, GPH 201, Global Public health, which will be offered by the Dept of Biology, CALS, as an inquiry course in Fall 2009. The second course proposed is a basic course in epidemiology/biostatistics. She formed working group across 6 colleges to develop a Master’s in Development Practice (similar to International Development); co-wrote and submitted pre-proposal to MacArthur Foundation for funds to establish the program with Dr. Heidi Hobbs. We were invited to submit a full proposal but decided to partner with TERI India and other global partners for a stronger application; pending decision on support (Lead at NCSU will be Dr. Heidi Hobbs, Director of the Master in International Studies, CHASS); proposal pending. Dr. Arasu is also working with Heidi Hobbs to develop a professional science master's focused on international development (bridging life sciences, natural sciences, social sciences and management). New course at Ohio State University based on 1 week selective "International Veterinary Medicine" at NC State University CVM. Dr. Arasu delivered a guest lecture on Dec 15, 2008, by videoconference to veterinary students at Ohio State University (course coordinator Dr. Wondwossen Gebreyes).


Jill Barnes is developing a summer workshop “Canine Anatomy” designed to aid in transition of incoming freshman students into the professional program.


Matthew Breen is serving his third year on the FCCCE, which has begun a complete reevaluation of the DVM curriculum at NC State. The activities of this committee required a considerable effort as we moved toward a faculty driven outline for change.


Gregg Dean has developed comparative medicine and translational research training program for specialty trained post-DVM PhD candidates.


Lloyd Fleisher is an ex officio member of the CVM Curriculum Committee, he has been actively involved in a major revision of the Veterinary teaching curriculum. Dr. Fleisher also serves on a subcommittee charged with devising novel testing paradigms for the new curriculum.


John Gadsby wrote 2 new lectures “Introduction to Endocrine Pharmacology” and “Drugs affecting Reproduction”, and presented them in VMB933 Veterinary Pharmacology as a guest lecturer, Fall 2008.


Troy Ghashghaei initiated the development of a new format of teaching the Neurophysiology portion of the Physiology course in the first year DVM curriculum.


Jon Horowitz developed and was the course coordinator of a new four credit graduate course “CBS771: Cancer Biology” that was completed by thirteen students in the Fall of 2008. This course was taught by six professors, two from MBS and four from the Dept. of Environmental and Molecular Toxicology, and received very strong evaluations from participating students. Dr. Horowitz wrote and presented 40% of the lectures in this course.


Lola Hudson - development/initiation of a new on line course in conjunction with Drs. Klesath (Zoology), Hardie, and our medical illustrator. This course is intended to ascertain that incoming students have a certain level of anatomical knowledge and medical terminology before they enter the rigorous professional curriculum. This course was offered in summer of 2008 and Dr. Klesath has received grade information from Dr. Hudson on the veterinary classes being compared for statistical analysis.


Chris McGahan continues to redesign curriculum in Veterinary Physiology.


Mark Papich serves on the College Curriculum Committee (FCCCE) (term started in the fall of 2007) as the department representative. This committee has been charged with reviewing, reorganizing, and proposing changes in the DVM curriculum to better prepare our future veterinarians. This committee meets every two weeks and the focus on curriculum evaluation will continue into next year.


In 2009, Dr. Papich published a new edition of a long-standing textbook for teaching veterinary pharmacology. He was one of the editors for the book, Veterinary Pharmacology and Therapeutics, 9th Edition, Wiley-Blackwell Publishing, Ames, Iowa, USA, 1524 pages; 2009. This book is now in its 9th edition and is a standard textbook for teaching veterinary pharmacology to students.


In 2009, Dr. Papich was one of the consulting editors for the book, Kirk’s Current Veterinary Therapy XIV, edited by Bonagura JD & Twedt DC, Saunders-Elsevier. This book is a widely-cited clinical textbook used by students, now in its 14th edition.


Lysa Posner serves on the subcommittee for PBL (Problem Based Learning), 2008-2009.


Ian Roberston’s ongoing improvement of VMB 976 course, for which he is the supervisor, involved generating extensive online quiz material via Blackboard Vista and generating other self directed learning resources.


Korinn Saker participated in meetings and discussion groups here at NCSU-CVM pertaining to development of the Wellness Training Program for DVM students. Dr. Saker also participated in the Deans Forum – Innovations in Education (November 2008) to discuss important issues that impact the veterinary curriculum.


Cliff Swanson was an invited participant and facilitator, AAVMC Educational Symposium, Washington DC, March 13-15, 2008.


Jeff Yoder, as course director for CBS565 Fundamentals of Biomedical Sciences, over the past 4 years, has gained an appreciation for the different educational backgrounds that the incoming CBS graduate students bring with them. It became clear that many students lacked an understanding of multiple standard cellular and molecular methods used in biomedical research. As co-course directors, Dr. Matthew Breen and Dr. Jeff Yoder have developed a new 1-credit graduate course to be offered every fall starting in 2009 (currently waiting approval from the Administrative Board of the Graduate School). This course, CBS570, Methods in Biomedical Sciences, will provide a 1 hr lecture each week on a variety of standard methods. Dr. Yoder will be providing lectures on DNA/RNA/protein analyses, PCR, cloning cDNAs, expression constructs, transgenesis, gene “knock-out” models and flow cytometry.


Dr. Yoder, as course director for CBS565 Fundamentals of Biomedical Sciences, over the past 4 years, has concluded that the overall course topics and lecture schedule in CBS565 needed to be rethought and reorganized. At a meeting of the teaching faculty for this course, it was agreed that more focus and continuity was needed for the lecture topics and a task force committee was appointed. When this committee met, it was agreed that each of the 5 Concentration Areas within CBS (Cell Biology, Pathology, Pharmacology, Infectious Disease and Population Medicine) should have equal representation in this course. Thus each Concentration Area Leader will be responsible for deciding the 4-5 lecture topics to be included in CBS565 and will identify the appropriate faculty members to present the lectures in this course. We will be implementing these modifications in the fall of 2009.


Clinician Scientist Focus Area (CSFA) has been a departmental initiative which continues to develop and grow.


Prema Arasu - served as Chair, Steering Committee, One Health Intellectual Exchange Group - committee convened in September 2008; inaugural seminar in January 2009 with subsequent, one seminar a month held at NC Biotechnology Center, targeting students in veterinary and human medicine ( as well as graduate students, public health) from NCSU, Duke, UNC. Dr. Arasu was responsible for selecting topics and speakers.


Matthew Breen is the leader of the Clinician Scientist Focus area and as such has continued to identify research oriented DVM students that could be encouraged to become involved in research activities at NCSU. Dr. Breen meet with the enrolled CSFA students one:one on a regular basis to gauge their feel for the program and to monitor their progress in the research aspects of their DVM program.


Gregg Dean provided a research experience as a selective for Austin Duncan a freshman DVM student.


John Gadsby, coordinator (and presenter) of “Research in Reproduction” research day within the one week “Introduction to Research at CVM” selective (VMB 990D) – Fall 2008.


Korinn Saker developed a feline mammary gland organ culture system to evaluate chemotherapeutic and selected nutrients. Dr. Saker also developed and procured funding for two educational programs in Clinical Nutrition. i) IAMS Rotating Nutrition Internship – a 1-year internship training in small animal disciplines as well as small animal clinical nutrition. Initial funding is for 2 years. ii) Nestle Purina Clinical Nutrition Residency – a 2-year clinical training program here at NCSU-CVM.


Introduction to Research at the CVM

“Introduction to Research at the CVM” (VMB 991D) is offered in the fall semester as a one-week selective and will be required for all students interested in the CSFA. Students are expected to take this selective in the fall of the 1st yr of the DVM curriculum. This selective will be open to any student interested in exploring the possibility of choosing the CSFA. All three departments participate in this Focus Area.


In this selective, mentors in the different areas of clinical and basic research experience will present a summary of ongoing projects in their laboratories. This selective will be divided into identifiable areas of research based on the group of participating mentors (i.e. oncology, neurology, therio, etc., ideally combining both basic and clinical aspects of research), with each group responsible for presenting their area of interest to the students. Students will be required to interview briefly with three potential mentors during the time of the selective. Students will also be required to prepare a personal statement indicating their personal and academic goals, their reasons for choosing the CSFA, and their reasons for pursuing a particular mentor opportunity.

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