College of veterinary medicine north carolina state university m. Christine McGahan, Professor and Department Head




НазваниеCollege of veterinary medicine north carolina state university m. Christine McGahan, Professor and Department Head
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ANNUAL REPORT


2009-2010


DEPARTMENT OF MOLECULAR BIOMEDICAL SCIENCES


COLLEGE OF VETERINARY MEDICINE



NORTH CAROLINA STATE UNIVERSITY


M. Christine McGahan, Professor and Department Head




Prepared May 2010




Table of Contents


Page
















Departmental Report

3

I.

Changes in Environment

3

II.

Compact Plan

3

III.

Diversity

4

IV.

Instructional Program

10

V.

Faculty

18

VI.

Students

19

VII.

Research

20

VIII.

Administration and Staff

21

IX.

Recommendations and concerns for the future

21

X.

The University’s Five Focus Areas

27

Appendix I

List of Faculty/EPA Employees Including Graduate Students

31

Appendix II

List of Administrative and Staff Personnel

32

Appendix III

Courses Offered by Departmental Faculty Including DVM courses

Presented by Departmental Faculty and Graduate Courses Offered by and Participated in by Departmental Faculty

35

Appendix IV

Clinical Service Offered by Departmental Faculty

37

Appendix V

Publications, Presentations, Intellectual Property by Departmental Faculty

63

Appendix VI

Professional Activities by Departmental Faculty (Includes Memberships on Research Grant and Study Reviews, Memberships on Editorial Boards, and Ad hoc Manuscript Reviews, Committee Memberships within MBS, CVM, NCSU, and National Committees

76

Appendix VII

Research Grants Awarded to Departmental Faculty

I. Change in Environment

Faculty retirement: no retirements

Faculty resignations: Prema Arasu – 5/24/2010; Adjunct appointment 5/24/2010

Faculty hires: Gabriela Seiler – Assoc Professor of Radiology; appointed 7/1/2009


The budget cuts of the past year and projected cuts for the upcoming year have left us with a loss of 4.5 faculty positions and over $100K in staff positions. This represents a cut in state-funded faculty positions of about 13%.

We are now in a serious situation when it comes to covering the teaching mission of the department. We are critically short in a number of areas, including Pharmacology, Toxicology, Cell Biology/Histology. The loss of staff positions also gravely undermines the teaching and research missions of the College. We now have only a handful of state-funded research tech support positions left, and it was necessary to RIF one of our two teaching techs who work in the Anatomy Lab. We are indeed in perilous times and facing even more cuts in the future. Quite frankly, there is nothing more to cut. Despite these terrible times, and decreasing federal resources, our faculty and staff continue to strive successfully for extramural dollars to keep their programs running. This is testimony to their skill and hard work, we indeed have a dedicated and talented pool of people in the department.


II. Compact Plan: For 2008-2010 the Compact Plan was developed at the College level.


III. Diversity


Kenneth Adler was awarded a supplement to his NIH grant for “underrepresented minorities” for Ms. Teresa Green, a graduate student in his laboratory. He is the PI on a grant submitted to NIH called IRACDA that supports partnering of NCSU with traditionally black colleges in the state and providing research resources for minority candidates.


Prema Arasu, within context of diversity strategies as defined by NCSU Office of Diversity (http://www.ncsu.edu/odi/initiatives/Diversity_Advisory.pdf), she has: 1) coordinated outreach meetings and seminars within North Carolina and with partner institutions in India focused on the multi-disciplinary intersection of livestock production, biofuels and health with NCSU faculty and students and external stakeholders (through USDA funded award; teamed with CVM Faculty Maria Correa and Isabel Gimeno and CALS faculty Vivek Fellner and Ratna Sharma); 2) served as Park Faculty Scholar for Class of 2011 and facilitating diversity experiences together with Professor Clifford Griffin, Political Science; 3) organized inter-institutional meetings with faculty from Durham Technical Community College, NC Central University and NC A&T University with NCSU and with other regional institutions (e.g. RTI International); 4) served as NCSU representative to the Triangle Global Health Consortium; 5) continued to serve on NCSU College of Management Biosciences Management/Industry (external) Advisory Board; 6) facilitated various international partnerships for NC State University including Zhejiang University and China Agricultural University in China, recruitment of graduate students from Malawi through a USAID sub-contract to NCSU; 7) coordinated conception and organization of NCSU Health and Well-being Initiative together with Dr. Mitzi Montoya (College of Management) and Dr. Liana Fryer (now Research Analyst with NCSU Research Office); and 8) coordinated and led NCSU's first Global Health Case Competition bringing together interdisciplinary teams of undergraduate and graduate students from different colleges to compete and develop an innovative solution for a global/local issue.


Jill Barnes, member Ad hoc Diversity Committee (NCSU CVM); Faculty Diversity Award, 2009; USDA, Veterinary Career Pathways Program, May 2009, mentored six minority students in the program in veterinary anatomy “short course”, consisted of 5 weeks of 7 hrs of instruction/week on the limbs/ thoracic cavity /head /abdominal cavity; and SAVE program, NC A&T students, heart dissection lab.


Gregg Dean, faculty mentor for NC State Initiative for Maximizing Student Diversity (IMSD); participation in DVM/PhD admissions, molecular biology training program, DVM/PhD training program, and GAANN program; recruited and hired undergraduate minority student, objective is to provide mentorship prior to application to DVM program.

Shila Nordone, 1) mentor, Project SEED, summer 2009. Project SEED, the American Chemical Society's social action program, places talented, disadvantaged high school students in research laboratories for 8-10 weeks during the summer to experience "hands-on" research; 2) the ability to have diverse universities at the student and faculty level has its roots in adequate education for minority children in our public schools. She currently serves as the Hill Street Homework Haven’s liaison to the Wake County Public School System. The Haven is located in SE Raleigh, and serves underprivileged African American children in K-12. They provide one-on-one tutoring and advocate for children at both the school level and in public policy at the county level.


Jorge Piedrahita, Co-PI in NIH training grant to bring minority undergraduate and graduates into sciences; PI is Trudy McKay. The program is “Initiative for Maximizing Student Diversity” (IMSD; http://www.ncsu.edu/grad/imsd/index.php) . He is a member of the steering committee and of the admission committee for this program. He participated as a panel member for the BFF “Building Future Faculty” program.


Barbara Sherry participated in the “Initiative for Maximizing Student Diversit” (IMSD) program at NCSU, funded by the NIH. The IMSD program is designed to increase the number of students from underrepresented minority groups who receive PhD's in the biomedical and behavioral sciences, and ultimately pursue research careers in these fields. Ms. Phoebe Cruz, an undergraduate student at NCSU who is part of this program, is conducting research in her laboratory.


Marcelo Rodriguez-Puebla has a minority supplement to his NIH Grant in support of Christopher Sistrunk.


IV. Instructional Program Initiatives including curriculum development and program review


Curriculum Development

MBS faculty are actively involved in the ongoing curricular review and revision. Efforts have been made by faculty to develop and introduce teaching innovations to enhance student problem-solving and communication abilities. This is particularly evident in the selective courses taught at the end of each semester, which provide a variety of offerings, which expand flexibility in the curriculum and new and varied experiences for students.


We are continuing to work on changes within existing courses to incorporate molecular medicine into the curriculum. We are continuing to work on the Physiology course (VMA 913 and 923) to include genomics and molecular medicine concepts, as well as to better align the subject matter in order to match more closely with Anatomy.


Prema Arasu facilitated NCSU's partnership with TERI India on new global Master’s in Development Practice through funding awarded to TERI by the MacArthur Foundation. She is serving as lead for the Global Health course to be offered in this new program in March 2011 which will also be imported back to NCSU.


Jill Barnes, “Introduction to the Veterinary profession”, course coordinator, summer 2009, an on-line course designed to better prepare first year vet students to anatomy and physiology.


Matthew Breen, serving his fourth year on the FCCCE. This committee has required a considerable time commitment as they embarked on a comprehensive reevaluation of the DVM curriculum at NC State.


Gregg Dean, directed comparative medicine and translational research training program for specialty trained post-DVM/PhD candidates. Initiated the incorporation of an online case based learning tool into VMP942. The “Diagnostic Pathway” program was developed by Dr. Holly Bender and colleagues. Dr. Bender will visit in June 2010 to facilitate the full implementation of the program.


Lloyd Fleisher, as an ex officio member of the CVM Curriculum Committee, has been actively involved in a major revision of the veterinary teaching curriculum. As course director of VBM 933, Introductory Pharmacology, he has been actively involved in the initial planning of the restructuring the veterinary curriculum in order to accommodate at least 100 students.


Troy Ghashghaei, initiated the development of a new format of teaching the Neurophysiology portion of the physiology course in the first year DVM curriculum.


Jon Horowitz, developed and is the course coordinator of a four credit graduate course, CBS771 “Cancer Biology”, that was completed by eight students in the Fall of 2009. This course was taught by six professors, two from MBS and four from the department of Environmental and Molecular Toxicology, and received very strong evaluations from participating students. He wrote and presented 40% of the lectures in this course.


Mark Papich, served on the College Curriculum Committee (FCCCE), term started in the fall of 2007, as the department representative. This committee has been charged with reviewing, reorganizing, and proposing changes in the DVM curriculum to better prepare our future veterinarians. This committee meets every two weeks and the focus on curriculum evaluation will continue into next year. In 2010, he completed the 3rd edition of the book on veterinary drugs, “Handbook of Veterinary Drugs”, published by Elsevier-Saunders. This is a widely used book by clinicians and students. It is in production and will be published in the fall of 2010. He was the first faculty member at the CVM to implement the new NCSU web-based course development software Moodle. His course is fully integrated with Moodle. The course web site contains practice quizzes for students, reference materials, resources, and teaching materials.


Lysa Posner, course-leader subcommittee for Curriculum Review 2009-2010.


Ian Roberston, ongoing improvement of VMB 976 course for which he is the supervisor. This involved generating extensive online quiz material via Blackboard Vista and generating other self directed learning resources.


Korinn Saker, participated in numerous meetings/discussion groups for program implementation for Outpatient Center Planning, which is targeted to be both a ‘service center’, as well as a ‘teaching-training’ center for house officers and veterinary students. Participated with VTH college faculty in initiative to evaluate and improve DVM curriculum - weekly meetings/seminars and discussion groups. Developed clinical nutrition course for extern program veterinary technicians including basic nutrition concepts and applied (clinical) concepts and techniques. It has become a mandatory component of the veterinary technician extern program here at the VTH. Presented the idea to create dual training program for house officers that provides clinical residency training in specialty (i.e. nutrition, etc) and MS in Adult Education. Discussions are ongoing between administrators of the CVM and College of Education. Discussions are ongoing between Korinn Saker and sponsor for the first dual residency MS, Adult Education training program.


Philip Sannes, actively participated in course coordinator meetings designed to develop changes in the curriculum.


Cliff Swanson, participating in DVM curriculum revision being conducted by course coordinators. Gave invited presentation related to teaching and learning in the clinical environment to this same group, Feb. 26, 2010.


Jeff Yoder, Graduate Education - CBS565 (F09) Course Director. He continues to be course director for and lecture in the graduate course CBS565, Fundamentals of Biomedical Sciences. As course director, he maintains the course web page, coordinates and administers exams and coordinates approximately 15 faculty members. Based on student evaluations for this course and with input from the CBS committee, a critical evaluation of CBS565 was performed in the spring of 2009 and changes to reorganize the lecture topics were implemented in the fall of 2009: these changes provided more focus and continuity for CBS565. CBS770 (S10) Lecturer. He continues to provide lectures in the graduate course CBS770, Cell Biology. CBS570 Co-Course Director, Matthew Breen and Jeff Yoder have developed a new one-credit course, CBS570, Methods in Biomedical Research, which is designed to teach incoming graduate students about different molecular methods. Jeff Yoder will be presenting six lectures on DNA, RNA, protein analyses, PCR strategies, cloning cDNAs, expression constructs, transgenic strategies and knock-out strategies. The intent was to begin offering this course in F09, but due to scheduling conflicts, it will be offered annually beginning F10. Veterinary Education, VMB913 (F09) Lecturer. He continues to provide two lectures on gene regulation for VMB913, Veterinary Physiology I.


Clinician Scientist Focus Area (CSFA) has been a departmental initiative which continues to develop and grow.


Prema Arasu, invited and hosted two professors from universities in China to conduct workshop on Traditional Chinese Veterinary Medicine at the North Carolina Veterinary Conference (for continuing education credit).


Matthew Breen, leader of the Clinician Scientist Focus area, has continued to identify research oriented DVM students that could be encouraged to become involved in research activities at NCSU. Dr. Breen meets with the enrolled CSFA students one:one on a regular basis to gauge their feel for the program and to monitor their progress in the research aspects of their DVM program.


John Gadsby, host/research mentor in his laboratory for 2 first year DVM students (Summer Kingery and Shama Dunlow) for the one week “Introduction to Research at CVM” selective (VMB 990D), Fall 2009.


Korinn Saker, utilized the newly developed feline mammary gland organ culture system to evaluate chemopreventive / chemotherapeutic aspects of selected nutrients. Designed and completed data collection for a catheter parenteral nutrition safety study to help establish ‘safe use’ parenteral feeding protocols for intensive care patients. Designed and completed study to evaluate efficacy (nutritional and safety) of various companion animal diets: including a frozen canine pet food, a unique enteral critical care diet for dogs and cats. Revised the clinical and research components of house officer, intern and resident, training programs in nutrition for: i.) IAMS Rotating Nutrition Internship – a 1 year internship training in small animal disciplines as well as small animal clinical nutrition; ii.) Nestle Purina Clinical Nutrition Residency, a 2 year clinical training program here at NCSU-CVM. Procured a second cycle of funding for IAMS Rotating Nutrition Internship. Funding obtained for 2–1yr interships. Procured funding for a 2-year Clinical Nutrition Residency training program at NCSU-CVM. As chair of the education committee of American College of Veterinary Nutrition: i.) created the Standard Core Nutrition Competencies as the benchmark for ‘need to know’ clinical nutrition skills for all veterinary graduates; ii.) Korinn Saker and 3 colleagues developed a full spectrum on-line veterinary nutrition course. The course is module driven to provide either a complete comprehensive, basics to clinical applications, course for veterinary students that do not have a nutrition course in their curriculum, or provide individual modules as CE materials for practicing veterinarian, or provide individual modules for pre-veterinary students requiring fundamental nutrition course as prerequisite for veterinary school application. Participated as one of the core group of nutrition specialists to develop the Veterinary Specialty Training program in Nutrition. This is one of several specialty certification programs for licensed veterinary technicians to obtain training in specialty areas, i.e. nutrition, critical care, oncology, surgery.

Introduction to Research at the CVM


“Introduction to Research at the CVM” (VMB 991D) is offered in the fall semester as a one-week selective and will be required for all students interested in the CSFA. Students are expected to take this selective in the fall of the 1st yr of the DVM curriculum. This selective will be open to any student interested in exploring the possibility of choosing the CSFA. All three departments participate in this Focus Area.


In this selective, mentors in the different areas of clinical and basic research experience will present a summary of ongoing projects in their laboratories. This selective will be divided into identifiable areas of research based on the group of participating mentors (i.e. oncology, neurology, therio, etc., ideally combining both basic and clinical aspects of research), with each group responsible for presenting their area of interest to the students. Students will be required to interview briefly with three potential mentors during the time of the selective. Students will also be required to prepare a personal statement indicating their personal and academic goals, their reasons for choosing the CSFA, and their reasons for pursuing a particular mentor opportunity.

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