Name Kenneth Nigel Timmis Date of Birth




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CURRICULUM VITAE OF KENNETH N. TIMMIS


Name Kenneth Nigel Timmis


Date of Birth February 16, 1946


Nationality British


Marital Status Married, one child


Education 1957-64 King's Norton Grammar School, Birmingham, U.K.


1964-67 Bristol University, U. K; awarded B.Sc. (Hons) Class I in Microbiology in 1967


1967-70 Department of Bacteriology, Bristol University, U.K; awarded Ph.D. in 1971


Career 1970-72 Postdoctoral Fellow, Lehrstuhl für Biologie der Mikroorganismen, Ruhr University, Bochum, FRG.


1972-73 Postdoctoral Fellow, Dept. of Molecular Biophysics and Bio­chemistry, Yale University, U.S.A.


1973-76 Research Associate, Dept. of Medicine, Stanford University, U.S.A.


1976-81 Head, Plasmid Group, Max Planck Institute for Molecular Genetics, W. Berlin, FRG.


1979 Habilitation in Microbiology and Molecular Biology, Free University, W. Berlin, FRG.


1981-1988 Professor, Dept. of Medical Biochemistry, University of Geneva, Switzerland


from 1988 Professor, Institute of Microbiology, Technical University Braunschweig


1988-2006 Director, Division of Microbiology, GBF - National Research Centre for Biotechnology/HZI - Helmholtz Centre for Infection Research, Braunschweig, Germany


From 2006 Head, Environmental Microbiology Laboratory, HZI, Braunschweig


Awards, Honours 1967-70 Medical Research Council Scholarship for Graduate Studies


1968 British Council European Scientific Exchange Fellowship


1970 Trinity College Dublin - University of Bristol Scientific Exchange Fellowship


1972-75 Helen Hay Whitney Foundation Postdoctoral Fellowship


Since 1983 Member, European Molecular Biology Organization


Since 1992 Fellow, American Academy of Microbiology


  1. Erwin Schrödinger Prize


2001 ISI Highly Cited Microbiology


Initiatives 1987 Founder and first Chairman of Council of the European Environmental Research Organization


Editorships 1987-1997 Journal of Bacteriology


1998-2006 Current Opinion in Biotechnology


Since 1998 Founding Editor, Environmental Microbiology


Since 2007 Founding Editor, Microbial Biotechnology


Member of 1982 Advisor, Scientific Working Group on Bacterial Commissions Enteric Infections, World Health Organization


1986 Advisor, Development of Vaccines against Shigellosis, World Health Organization


1986-1988 Chairman, Section Genetic Engineering, Swiss Commis­sion for Biological Safety


1987-1990 Member, Scientific Working Group on Filariasis, World Health Organization


1988-1990 Member, SCOPE-COGENE Scientific Advisory Committee on Environmental Biotechnology


1988-1990 Member, International Scientific Advisory Committee, UNEP/USSR Project "Microbial Technologies for Degradation of Persistent Pollutants"


1990 Member, CEC Ad Hoc Group of Experts on "Biotechnology for Improvements in Conservation and Utilization of Biological Diversity"

1990-1991 Member, U.S. Dept. of Energy Expert Panel "Assessment of Research Needs for Fossil Energy Biotechnology".


1991 Chairman, CEC Ad Hoc Group of Experts on "Exploration of so far hidden microbial communities".


1992 Member, American Academy of Microbiology Panel on Scientific Foundations of Bioremediation (Workshop, Iowa City, April, 1992)


1992 Member, Commission for Evaluation of the Department of Biotechnology, Institut Pasteur, Paris


1992-1995 Chairman, Review Panel for BMFT Programme: Biological Safety - GMO Release Research


1993 Representative of EC in OECD Workshop on "R and D Priorities in Environmental Biotechnology", for recom­mendations on "Biotechnology for a Clean Environment"


1993-1994 Member, International Scientific Advisory Board, Centro de Investigaciones Biologicas (CIB), Madrid


Since 1993 Member, Scientific Advisory Committee, National Biotechnology Centre (CNB), Madrid.


1995-2005 Member, CNRS Commission ATIPE Microbiologie


1996 Member of EMBO Committee to evaluate Molecular Biology and Biotechnology in Finland, and Chairman of Panel D: Microbiology, Microbial Pathogens and Immunology.


1998 Member, Expert Committee for Evaluation of Microbiology at the University of Lausanne


    1. Member, Evaluation Committee of CNB, Madrid


2001-2004 International Initiatives Committee, American Academy of Microbiology


2002-2006 Member, Scientific Advisory Board, Kluyver Centre for Genomics of Industrial Fermentation


2005 Member, EMBO Evaluation Committee, CSIC institutes, Spain


2007 Member, Evaluation Committee, Dept. of Microbiology, Institut Pasteur


from 2008 Member, Scientific Advisory Board, CIB, Madrid


Symposium/Course

Organizer

  1. International Symposium "Plasmids and other

Extrachromosomal Genetic Elements", W. Berlin, FRG

1979 EMBO Laboratory course "Plasmids: a Course in Advanced Techniques", Erlangen, FRG


1979 International Symposium "Plasmids of Medical, Environmental and Commercial Importance", Spitzingsee, FRG.


1983 EMBO Laboratory Course: "Plasmids, a Course in Advanced Techniques", Bielefeld, FRG


1986 EMBO Workshop: "Genetic Manipulation of Pseudomonads - Applications in Biotechnology and Medicine", Geneva, Switzerland


1990 EERO-GBF International Symposium "Environmental Bio­technology", Braunschweig, FRG.


1990 EERO Workshop "Molecular Microbial Ecology", Königslutter, FRG.


1994 GBF-BMFT Workshop "Molecular Microbial Ecology", Wolfenbüttel, FRG


1995 Juan March Foundation Workshop "Biodegradation of Xenobiotics", Madrid, Spain


1996 UIB-GBF-CSIC-TUB Symposium "Biodegradation of Organic Pollutants", Mallorca, Spain

1996 GBF Symposium “Antibody Technology and Applications in Health and Environment” Braunschweig, FRG.

1996 Biotec 96 Symposium “Environmental Biotechnology”, Düsseldorf, FRG.


1997 GBF-Dechema-DFG Research Unit Hamburg Workshop “Innovative Potential of Advanced Biological Systems for Remediation”, Hamburg, FRG


  1. “Bioremediation: Entwicklungsstand-Anwendungen-Perspektiven”, Munster, FRG




  1. German Microbiology Society (VAAM) Annual Meeting, Braunschweig


2004 ESF Workshop Environmental Genomics and Environmental Metagenomics, Granada, Spain



Member of 1987-1989 Second International Symposium on

Symposia Pseudomonads (Chicago, 1989)

Scientific

Advisory 1988 European Conference on Biotechnology (Verona,

Boards 1988)


1990-1991 Third International Symposium on Pseudomonads (Trieste, 1991)


1990-1992 Sixth International Symposium on Microbial Ecology (Barcelona, 1992)


1991-1992 The Biosafety Results of Field Tests of Genetically Modified Plants and Microorganisms (Goslar, 1992)


1991-1992 EERO Workshop on "Bioinorganic and Biotechnological Aspects of Environmental Chemistry (Florence, 1992)


1992-1993 Fourth International Symposium on Pseudomonads (Vancouver, 1993)


1994-1995 Fifth International Symposium on Pseudomonads, (Japan 1995)


1994-1996 IUMS VIIIth. International Congresses of Bacteriology and Applied Microbiology (Jerusalem, 1996)


1996-1998 42nd Oholo Conference “Novel Approaches for Bioremediation of Organic Pollution (Eilat, 1998)


1997-1999 6th International Symposium on Bacterial Genetics and Ecology (Florence, 1999)


    1. IUMS IXth International Congress of Bacteriology and Applied Microbiology (Sydney, Australia, 1999)




    1. 9th International Symposium on Microbial Ecology (Amsterdam, 2001)




    1. IUMS Xth International Congress of Bacteriology and Applied Microbiology (Paris, 2002)




    1. XVth Lancefield International Symposium on Streptococci and Streptococcal Diseases (Goa, 2002)


2002-2003 International Workshop Metagenomics 2003 - from microbial diversity to function, Darmstadt, Germany


Member of American Society for Microbiology

Professional

Societies Biochemical Society, U.K.


Gesellschaft für Genetik


Verein für Allgemeine und Angewandte Mikrobiologie


DECHEMA


Teaching 1967-1970 Bristol University

Activities

Laboratory courses on microbial genetics,

applied microbiology


Lecture courses on bacteriocins


Tutorials on microbiology


Extramural courses entitled "Microbes and Man" and "Microbiology in Schools"


1971-1972 Ruhr-Universität Bochum


Lecture courses on microbial physiology, gene regulation


Laboratory courses on general microbiology, microbial physiology


Seminars on microbiology


    1. Free University Berlin


Lecture courses on extrachromosomal elements, microbiology of environmental pollution


Laboratory courses on gene cloning


Seminars on molecular genetics


1981-1988 University of Geneva


Lecture courses on biochemistry, especially structure and function of nucleic acids, gene regulation, recombinant DNA and medical aspects of nucleic acids, cellular growth and oncogenes


Laboratory courses on biochemistry


From 1988 Technical University Braunschweig


Lecture and Laboratory courses on microbial physiology and ecology


Seminars on microbial ecology

PUBLICATIONS


  1. Timmis, K. 1970. Studies with purified colicins. Ph. D. Thesis, University of Bristol.


2 Timmis, K. 1972. Purification and characterization of colicin D. J. Bacteriol. 109: 12-20.


3. Timmis, K. and A. J. Hedges. 1972. The killing of sensitive cells by colicin D. Biochim. Biophys. Acta 262: 200-207.


4. Timmis, K. and U. Winkler. 1973. Isolation of covalently-closed circular deoxyribonucleic acid from bacteria which produce exocellular nuclease. J. Bacteriol. 113: 508-509.


  1. Winkler, U. and K. Timmis. 1973. Pleiotropic mutations in Serratia marcescens which increase the synthesis of certain exocellular proteins and the rate of spontaneous prophage induction. Molec. Gen. Genet. 124: 197-206.




  1. Timmis, K. and U. Winkler. 1973. Gene dosage studies with pleiotropic mutants of Serratia marcescens superactive in the synthesis of marcescin A and certain other cellular proteins. Molec. Gen. Genet. 124: 207-217.




  1. Timmis, K., G. Hobbs, and R. C. W. Berkeley. 1974. Chitinolytic clostridia isolated from marine mud. Can. J. Microbiol. 20: 1284-1285.




  1. Timmis, K., P.W. Early, and D. A. Marvin. 1974. Filamentous bacterial viruses. IX. Protein synthesis inhibitors and DNA replication. Biochem. Biophys. Res. Commun. 57: 263-270.




  1. Timmis, K. and D. A. Marvin. 1974. Filamentous bacterial viruses. XV. DNA replication and abortive infection. Virology 59: 281-292.




  1. Timmis, K. and D. A. Marvin. 1974. Filamentous bacterial viruses. XVI. Inherent temperature sensitivity of gene 5 protein and its involvement in abortive infection. Virology 59: 293-300.




  1. Timmis, K., F. Cabello, and S. N. Cohen. 1974. Utilization of two distinct modes of replication by a hybrid plasmid constructed in vitro from separate replicons. Proc. Nat­. Acad. Sci. USA. 71: 4556-4560.




  1. Timmis, K., F. Cabello, and S. N. Cohen. 1975. Cloning, isolation and characterization of replication regions of complex plasmid genomes. Proc. Nat. Acad. Sci. USA. 72: 2242-2246.




  1. Cabello, F., K. Timmis, and S. N. Cohen. 1976. Replication control in a composite plasmid constructed by in vitro linkage of two distinct replicons. Nature. 259: 285-290.




  1. Timmis, K., F. Cabello, and S. N. Cohen. 1976. Covalently closed circular DNA molecules of low superhelix density as intermediate forms in plasmid replication. Nature. 261: 512-516.




  1. Skurray, R. A., M. S. Guyer, K. Timmis, F. Cabello, S. N. Cohen, N. Davidson, and A. J. Clark. 1976. Replication region fragments cloned from Flac+ are identical to EcoRI fragment f5 of F. J. Bacteriol. 127: 1571-1575.




  1. Timmis, K., F. Cabello, and S. N. Cohen. 1977. Molecular cloning of plasmid DNA: properties of recombinant plasmids in transformed bacteria. In Modern Trends in Bacterial Transformation and Transfection, Eds. A. Portoles, R. Lopez and M. Espinosa, Elsevier, Amsterdam, 263-276.




  1. Timmis, K., F. Cabello, and S. N. Cohen. 1977. Properties and regulation of DNA replication origins and associated functions in multi-origin replicons. In Plasmids-Medical and Theoretical Aspects. Eds. S. Mitsuhashi, L. Rosival and V. Krcméry, Avicenum, Prague and Springer Verlag, Berlin-Heidelberg-New York, 417-424.




  1. Cohen, S. N., F. Cabello, A. C. Y. Chang, and K. Timmis. 1977. DNA cloning as a tool for the study of plasmid biology. In Recombinant Molecules: Impact on Science and Society. Eds. R. F. Beers, Jr. and E. G. Bassett, Raven Press, New York, 91-105.




  1. Cohen, S. N., F. Cabello, M. Casadaban, A. C. Y. Chang, and K. Timmis. 1977. DNA cloning and plasmid biology. In Molecular Cloning of Recombinant DNA. Academic Press, New York, 35-58.




  1. Timmis, K. N., F. Cabello, and S. N. Cohen. 1978. Cloning and characterization of EcoRI and HindIII restriction endonuclease-generated fragments of antibiotic resistance plasmids R6-5 and R6. Molec. Gen. Genet. 162: 121-137.




  1. Timmis, K. N., F. Cabello, I. Andrés, A. Nordheim, H. J. Burkardt, and S. N. Cohen. 1978. Instability of plasmid DNA sequences: Macro and Microevolution of the antibiotic resistance plasmid R6-5. Molec. Gen. Genet. 167: 11-19.




  1. Timmis, K. N., S. N. Cohen, and F. Cabello. 1978. DNA cloning and the analysis of plasmid structure and function. Prog. Molec. Subcell. Biol. 6: 1-58.




  1. Timmis, K. N., I. Andrés, F. Cabello, R. M. Synenki, S. N. Cohen, and H. J. Burkhardt. 1978. Replication functions of antibiotic resistance plasmid R6-5 and fertility plasmid F`
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