Curriculum and Syllabus for M. Tech. Industrial Biotechnology (revised in 2010 (bos)




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Dr. M.G.R. University


Dept. of Biotechnology


Curriculum and Syllabus for M.Tech. Industrial Biotechnology (revised in 2010 (BOS)


Preamble

  1. This course will offer specialization and hands on practical training with a potential for job placement in Biotechnology Industry.

  2. Eligibility: Candidates with an M.Sc. In Biotechnology, Botany, Zoology, Microbiology, Biochemistry or any of Life Science oriented subjects; 4-year professional courses such as B.Tech. Biotechnology, Industrial Biotechnology, Chemical Engineering, B.Pharm. B.V.Sc. or M.B.B.S. or Agriculture.

  3. The total credits for this course will be 70.

4.    The first Semester will teach the basic papers required for Biotechnology.

Bridge courses: A Chemical Engineering basic paper is mandatory for M.Sc. students; Chemical Engineering and B.Pharm candidates must take Genetics paper.   The others may opt for a Maths course;

  1. Intensive Laboratory courses in Biochemical Techniques and Microbial Techniques will be offered in the first Semester.

  2. In the Second Semester, courses will be offered in application oriented papers. There will be 4 core papers and 1 Electives followed by 2 Labs.

7.    In the third Semester, the candidates will take 3 core and 2 elective papers and 1 lab course.   This Semester will include a project pre-preparation and literature review.

8.    The last Semester will be entirely a project which will be marked based on a viva voce and Project report.

9. The same course can also be offered in Part-time mode, where the course will be spread over 6 Semesters.

10. If required students may opt for additional credits from other Dept.   However they will be included as a criteria for passing M.Tech. Industrial Biotechnology only if approved by the Board that this is considered part of Biotechnology.


Curriculum for M.Tech. Industrial Biotechnology (Part Time)

Credit Distribution


Semester

Credits

I

22

II

22

III

22

IV

9

TOTAL

75



I Semester

S.No.

Code

Course

L

T

P

C

1

MBT101

Advanced Microbiology

3

1

0

4

2

MBT107/109

Cell & Molecular Biology

3

1

0

4




3

MBT113

Microbial Techniques Lab

0

0

6

2

Bridge Courses (any one will be given)

4

MBTB101

Genetics

3

0

0

3




MBTB103

Basic Principles of Chemical Engineering

3

0

0

3




MBTB105

Mathematics

3

0

0

3







TOTAL

15

3

12

22


II Semester

S.No.

Code

Course

L

T

P

C

5

MBT106

Quantitative Methods

3

0

0

3

6

MBT103

Biochemistry and Enzymology

3

1

0

4

7

MBT105

Instrumentation Methods

3

0

0

3




8

MBT111

Biochemical Techniques Lab

0

0

6

2







TOTAL

9

1

6

12



III Semester

S.No.

Code

Course

L

T

P

C

9

MBT102

Genetic Engineering

3

1

0

4

10

MBT104

Bioinformatics

3

1

0

4




11

MBT110

Genetic Engineering Lab

0

0

6

2

ELECTIVE-I

12

MBTE02

Biology of the Immune System

3

0

0

3

13

MBTE04

Food Technology

3

0

0

3







TOTAL

12

2

6

16



IV Semester

14

MBT108

Fermentation Technology

3

1

0

4

15

MBT201

Genomics and Proteomics

3

1

0

4




16

MBT112

Fermentation Technology Lab

0

0

6

2







ELECTIVE-II













17

MBTE213

Biotechnology of Animal Production

3

0

0

3

18

MBTE211

Separation Techniques

3

0

0

3







TOTAL

12

2

6

16



V SEMESTER

19

MBT203

Animal and Plant Tissue Culture

3

1

0

4

20

MBT205

Intellectual Property Rights in Biotechnology

3

0

0

3




21

MBT207

Tissue culture Lab

0

0

6

2

22

MBT307

Project Phase I

3

0

0

3







ELECTIVE - III













23

MBTE217

Stem cells in Healthcare

3

0

0

3

24

MBTE201

Cellular and Molecular Diagnostics

3

0

0

3







TOTAL

15

1

6

18



SYLLABUS-I Semester


MBT101 Advanced Microbiology 3 1 0 4


Unit 1: New approaches to Bacterial taxonomy, determination and significance of DNA

Base composition, nucleic acid hycridization, RNA fingerprinting, bacterial phylogeny.


Unit 2: Metabolic diversity of aerobic heterotrophs – mechanisms in uptake of substrates

Entner-Doudoroff pathway, sugar degradation via Pentose Phosphate cycle, methyl glyoxal bypass, diversity in energy metabolism.


Unit 3: Bacterial Fermentation – Alcohol fermentation, lactate fermentation, buatyrate &

butanol –acetone fermentation, Anaerobic food chains; Chemolithotrophic and phototropic metabolism.


Unit 4: Degradation of natural substances – Cellulose degradation, microbial conversion

in the rumen, xylan degradation, degradation of starch, fructans, mannan, pectin, agar, chitin, lignin; formation of humus, utilization of hydrocarbons – methane, ethane, propane, butane, aromatic hydrocarbons, xenobiotics.


Unit 5: Biodeterioration control and soil, waste and water management – Indicator microorganisms, fouling biofilms, treatment of solid waster, landfills, composting, treatment of liquid waste, biological oxygen demand.


References:

  1. General Microbiology, Fifth edition, (2006), Stanier RY, Ingraham JL, Wheels ML and RP Painter, Macmillan Press.

  2. Bacterial Metabolism, 2nd Edition (1986) Gerhard Gottschalk, Springer Verlag.

  3. Microbial Ecology – Fundamentals and Applications, 4th Edition, (2005), Atlas RM and R Bartha.

  4. General Microbiology, 7th Edition (1992), Hans G. Schlegel, Cambridge University Press.



MBT109/107 CELL AND MOLECULAR BIOLOGY 3 1 0 4

UNIT 1.INTRODUCTION

The cell: A macromolecular assembly, Cellular compartmentization, Organellar architecture. The Nucleus: Chromosomal DNA and its packaging, the global structure of Chromosomes, Chromosome replication, RNA synthesizing and RNA processing, the organization and evolution of the nuclear genome, Cytoskelton. DNAStructure, RNAstructure, organization of the bacterial chromosome, organization of eukaryotic chromosome,
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