University of California San Francisco, School of Medicine, Howard Hughes Medical Institute

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Christoph W. Turck

Christoph W. Turck, Ph.D.

Professor of Biochemistry


  1. M.Sc. (Dipl. Chem.), Chemistry

University of Aachen, Germany

1983 Ph.D. (Dr. rer. nat.), Chemistry

Department of Macromolecular Chemistry

University of Aachen, Germany


Max Planck Institute of Psychiatry

2002 – Present Head, Proteomics and Biomarkers

2003 – Present Adj. Professor

Department of Biochemistry, University of Munich

2004 – Present Faculty

International Max Planck Research School of Life Sciences

2009 – Present Faculty

Graduate School of Systemic Neurosciences

University of California San Francisco, School of Medicine, Howard Hughes Medical Institute

2000 – 2002 Professor, Department of Medicine

1993 – 2002 Associate Investigator, Cardiovascular Research Institute

1986 – 2002 Director, Protein Structure Laboratory

Howard Hughes Medical Institute

1994 – 2000 Associate Professor, Department of Medicine

1988 – 1994 Assistant Professor, Department of Medicine

1986 – 1988 Instructor, Department of Medicine

Roche Institute of Molecular Biology

1983 – 1986 Postdoctoral Fellow, Department of Cell Biology
Advisor: Dr. David R. Webb

University of Aachen

1982 – 1983 Research Associate, Department of Macromolecular Chemistry

1981 – 1982 Research Associate, German Wool Research Institute


1978 Industrial Traineeship (IAESTE), Volvo, AB, Research and Development. Göteborg, Sweden

1975 Industrial Traineeship (IAESTE), Hellenic Refinery, Quality Control. Athens, Greece


fNIH Biomarkers Consortium, Neuroscience Steering Committee

EU Innovative Medicines Initiative, NEWMEDS, Scientific Advisory Board

Association of Biomolecular Research Facilities, Metabolomics Research Group

American Society for Mass Spectrometry, Pharmaceuticals Interest Group

Biomarkers in Medicine, Editorial Board


Wilhelm Borchers Medal, University of Aachen, 1983

Postdoctoral Fellowship, Roche Institute of Molecular Biology, 1983 1986

Research Grant, Scleroderma Society, 1987-1988

Individual Investigator Research Grant, Academic Senate, UCSF, 1987-1988

Research Evaluation and Allocation Committee, UCSF, 1988-1989

United Scleroderma Foundation, Watsonville, CA, 1988-1990

American Heart Association Research Grant, 1993-1996

American Heart Association, California Affiliate Research Grant, 1996-2001

National Science Foundation, Research Award, 1998-2001

Australian Research Council, Research Grant, Partner Investigator, 2002-2004

Bavaria California Technology Grant, 2004-2005

BMBF National Genome Research Network, Neuronet, 2004-2008

BMBF National Genome Research Network, Exploratory Project Grant, 2004-2008

BMBF QuantPro-Quantitative Analysis of Dynamic Processes in Living Systems, 2006-2011

BMBF, National Genome Research Network Plus, MooDS, 2008-2013

BMBF, Molecular Diagnostics, 2009-2011


American College of Neuropsychopharmacology

American Society of Mass Spectrometry


American Society for Biochemistry and Molecular Biology

German Chemical Society

German Proteome Society


1. Turck, CW and Berndt, H. (1981) Synthesis of defined peptide derivatives by aminolysis of 3 [N acyl peptidyloxy] 2 hydroxy N alkylbenzamides at elevated temperatures. Part I: Hoppe Seyler's Z Physiol Chem 362:821 828. [Pubmed]

2. Krupen, K, Turck, CW, Stein, S, Kapp, JA and Webb, DR. (1985) Purification of antigen specific suppressor factors. Methods Enzymol 116:325-340. DiSabato, G., Langone, J.J. and VanVunakis, A., eds., Academic Press, New York. [Pubmed]

3. Turck, CW, Kapp, JA and Webb, DR. (1985) Purification and characterization of a second order monoclonal T cell suppressor factor specific for L glutamic acid60 L alanine30 L tyrosine10. J Immunol 135:3232 3237. [Pubmed]

4. Turck, CW, Kapp, JA and Webb, DR. (1986) Structural analyses of a monoclonal heterodimeric suppressor factor specific for L glutamic acid60 L alanine30 L tyrosine10. J Immunol 137:1904 1909. [Pubmed]

5. Webb, DR, Kapp, JA, Krupen, K, Pierce, CW, Sorensen, CM and Turck, CW. (1986). Antigen specific suppressor factors: Current perspectives. In: Mediators of Immune Regulation and Immunotherapy. Singhal, SK and Delovitch, TL, eds., Elsevier Press.

6. Webb, DR, Kapp, JA, Krupen, K, Pierce, CW, Sorensen, CM and Turck, CW (1986) Factors from T suppressor cells: Current status and perspectives. In: Advances in Immunopharmacology, Proc. of the 3rd Intern. Immunopharmacology Meet.

7. Aliakbari, J, Sreedharan, SP, Turck, CW and Goetzl, EJ. (1987) Selective localization of vasoactive intestinal peptide and substance P in human eosinophils. Biochem Biophys Res Comm 148:1440 1445. [Pubmed]

8. Loh, EY, Lanier, LL, Turck, CW, Littman, DR, Davis, MM, Chien, Y H and Weiss, A. (1987) Identification and sequence of a fourth human T cell antigen receptor chain. Nature 330:569 572. [Pubmed]

9. Turck, CW, Dohlman, JG and Goetzl, EJ. (1987) Immunological mediators of wound healing and fibrosis. J Cell Physiol (Suppl.) 5:89 93. [Pubmed]

10. Webb, DR, Turck, CW, Mensi, N, Kapp, JA and Kraig, E. (1987) Structural relationships among antigen specific suppressor factors and the T cell antigen receptor for the terpolymer L glutamic acid60 L alanine30 L tyrosine10. J Cell Biochem (Suppl.S11D) 35:222. [Wiley Interscience]

11. Beisiegel, U, Weber, W, Havinga, JR, Ihrke, G, Hui, DY, Wernette Hammond, ME, Turck, CW, Innerarity, TL and Mahley, RW. (1988) Apolipoprotein E binding proteins isolated from dog and human liver. Arteriosclerosis 8:288 297. [Pubmed]

12. Goetzl, EJ, Sreedharan, SP and Turck, CW. (1988) Structurally distinctive vasoactive intestinal peptides from rat basophilic leukemia cells. J Biol Chem 263:9083 9086. [Pubmed]

13. Turck, CW, Tom, JW, Kennedy, PW and Goetzl, EJ. (1988) Isolation and partial characterization of a fibroblast activating factor generated by U937 human monocytes. J Immunol 141:1225 1230. [Pubmed]

14. Goetzl, EJ, Finch, RJ, Peterson, KE, Turck, CW and Sreedharan, SP. (1989) Mast cell and basophil mediation of lymphocyte functions. In: Mast cell and basophil differentiation and function in health and disease. Galli, SJ and Austen, KF., eds., Raven Press, New York, 247 254.

15. Goetzl, EJ, Kodama, KT, Turck, CW, Schiogolev, SA and Sreedharan, SP. (1989) Unique pattern of cleavage of vasoactive intestinal peptide by human lymphocytes. Immunol 66:554 558. [Pubmed]

16. Goetzl, EJ, Sreedharan, SP, Turck, CW, Bridenbaugh, R and Malfroy, B. (1989) Preferential cleavage of amino  and carboxyterminal oligopeptides from vasoactive intestinal polypeptide by human recombinant enkephalinase (Neutral endopeptidase, EC Biochem Biophys Res Comm 158:850 854. [Pubmed]

17. Goetzl, EJ, Turck, CW, Peterson, KE, Finch, RJ, Kodama, KT, Adelman, DC and Sreedharan, SP. (1989) Neuromediators of immunity and inflammation. In: Progress in Immunol. Melchers, F., ed., Springer Verlag, Berlin, 772-779.

18. Kissel, JA, Fontaine, RN, Turck, CW, Brockman, HL and Hui, DY. (1989) Molecular cloning and expression of cDNA for rat pancreatic cholesterol esterase. Biochem Biophys Acta 1006:227-236. [Pubmed]

19. McGillis, JP, Park, A, Rubin Fletter, P, Turck, CW, Dallman, MF and Payan, DG. (1989) Corticotropin releasing factor stimulates rat lymphocyte proliferation. J Neurosci Res 23:346 352. [Pubmed]

20. Turck, CW, Kennedy, PW, Schiogolev, SA and Goetzl, EJ. (1989) Diverse responses of human fibroblasts to a highly purified fibroblast activating factor (FAF) from the U937 line of human monocytes. Immunol 68:410-415. [Pubmed]

21. Adolff, CA, Golden, JA, Gamsu, G, Goetzl, EJ and Turck, CW. (1990) Reduction in pulmonary fibroblast-stimulating activity as an index of response to treatment of interstitial lung diseases. New England J Med 322:1890-1891. [Pubmed]

22. Baumhueter, S, Mendel, DB, Conley, PB, Kuo, CJ, Turck, CW, Graves, MK, Graves, MK, Courtois, G and Crabtree, GR. (1990) HNF-1 contains a homeobox and shares two sequence motifs with the POU domain proteins. Genes Dev 4:372-379. [Pubmed]

23. Goetzl, EJ, Grotmol, T, Van Dyke, RW, Turck, CW, Wershil, B, Galli, SJ. and Sreedharan, SP. (1990) Generation and recognition of vasoactive intestinal peptide by cells of the immune system. Ann NY Acad Sci 594:34-44. [Pubmed]

24. Mensi, N, Webb, DR, Turck, CW and Peltz, GA. (1990) Characterization of Borrelia burgdorferi proteins reactive with antibodies in synovial fluid of a patient with lyme arthritis. Infect Immun 58:2404-2407. [Pubmed]

25. Adolff, CH, Kennedy, PW, Golden, JA, Goetzl, EJ and Turck, CW. (1991) Growth factor gene expression in cells from bronchoalveolar lavage fluids. Inflammation 15: 259-268. [Pubmed]

26. Demeter, J, Medzihradszky, D, Kha, H, Goetzl, EJ and Turck, CW. (1991) Isolation and partial characterization of the structures of fibroblast activating factor-related proteins from U-937 cells. Immunol 72:350-354. [Pubmed]

27. Escobedo, JA, Kaplan, DR, Kavanaugh, WM, Turck, CW and Williams, LT. (1991) A PI3 kinase binds to PDGF receptors through a specific receptor sequence containing phosphotyrosine. Mol Cell Biol 11:1125-1132. [Pubmed]

28. Goetzl, EJ, Turck, CW and Sreedharan, SP. (1991) Production and recognition of neuropeptides by cells of the immune system. In, Pseuchoneuroimmunolgy. Ader, R, Felten, DL and Cohen, N., eds., Academic Press, Orlando, FL., 263-282.

29. McCrea, PD, Turck, CW and Gumbiner, B. (1991) A homolog of the armadillo protein in Drosophila (Plakoglobin) associated with E-cadherin. Science 254:1359-1361. [Pubmed]

30. Mitsuhashi, M, Akitaya, T, Turck, CW and Payan, DG. (1991) Amyloid beta protein substituent peptides do not interact with the substance P receptor expressed in cultured cells. Mol Brain Res 11:177-180. [Pubmed]

31. Parnet, P, Mitsuhashi, M, Turck, CW, Kerdelhue, B and Payan, DG. (1991) Tachykinin receptor cross-talk - immunological crossreactivity between the external domains of the substance-K and substance-P receptors. Brain Behav Immun 5:73-83. [Pubmed]

32. Shanafelt, M-C, Hindersson, P, Soderberg, C, Mensi, N, Turck, CW, Webb, DR, Yssel, H and Peltz, G. (1991) T cell and antibody reactivity with the B. Burgdorferi 60 kD heat shock protein in lyme arthritis. J Immunol 146:3985-3992. [Pubmed]

33. Turck, CW, Herrmann, J, Escobedo, JA and Williams, LT. (1991) Identification of phosphotyrosine residues during protein sequence analysis. Pept Res 4:36-39. [Pubmed]

34. Williams, LT, Escobedo, JA, Fantl, W, Turck, CW and Klippel, A. (1991) Interactions of growth factor receptors with cytoplasmic signaling molecules. In: Cold Spring Harb Symp Quant Biol 56:243-250. [Pubmed]

35. Yu, YL, Golden, JA, Migchielsen, AAJ, Goetzl, EJ and Turck, CW. (1991) Relative quantification of collagen mRNA in fibroblasts by a radioactive polymerase chain reaction technique. J Clin Lab Anal 5:262-267. [Pubmed]

36. Blobel, CP, Wolsberg, TG, Turck, CW, Myles, DG, Primakoff, P and White, JM. (1992) A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356:248-252. [Pubmed]

37. Chan, AC, Iwashima, M, Turck, CW and Weiss, A. (1992) ZAP-70: A 70kD protein tyrosine kinase that associates with the TCR ζ chain. Cell 71:649-662. [Pubmed]

38. Fantl, WJ, Escobedo, JA, Martin, GA, Turck, CW, del Rosario, M, McCormick, F and Williams, LT. (1992) PDGF receptor binds to PI3 kinase and GAP through distinct tyrosine-containing sequences and with functional consequences for mitogenesis. Cell 69:413-423. [Pubmed]

39. Gold, MR, Chan, VW-F, Turck, CW and DeFranco, AL. (1992) Membrane immunoglobulin crosslinking regulates phosphatidylinositol 3-kinase in B lymphocytes. J Immunol 148:2012-2022. [Pubmed]

40. Näthke, IS, Heuser, J, Lupas, A, Stock, J, Turck, CW and Brodsky, FM. (1992) Folding and trimerization of the clathrin triskelion hub. Cell 68:899-910. [Pubmed]

41. Scarborough, RM, Naughton, M, Teng, W, Hung, DT, Rose, J, Vu, T-KH, Wheaton, VI, Turck, CW and Coughlin, SR. (1992) Tethered ligand agonist peptides: structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function. J Biol Chem 267:13146-13149. [Pubmed]

42. Shanafeldt, M-C, Anzola, J, Soderberg, C, Yssel, H, Turck, CW and Peltz, G. (1992) Epitopes on the outer surface protein A of borrelia burgdorferi recognized by antibodies and T cells of patients with lyme disease. J Immunol 148:218-224. [Pubmed]

43. Turck, CW. (1992) Identification of phosphotyrosine residues in peptides by high performance liquid chromatography online derivative spectroscopy. Pept Res 5: 156-160. [Pubmed]

44. Yu, Y-L, Kha, H, Golden, JA, Migchielsen, AAJ, Goetzl, EJ and Turck, CW. (1992) An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist. J Exp Med 175:1073-1080. [Pubmed]

45. Gu, Y, Turck, CW and Morgan, DO. (1993) Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature 366:707-710. [Pubmed]

46. Hagman, J, Belanger, C, Travis, A, Turck, CW and Grosschedl, R. (1993) Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev 7:760-773. [Pubmed]

47. Hahm, K, Kim, G, Turck, CW and Smale, ST. (1993) Isolation of a murine gene encoding a nucleic acid-binding protein with homology to HNRNP-K. Nucleic Acids Res 11:3894. [Pubmed]

48. Herrmann, J, Turck, CW, Atchison, RE, Huflejt, ME, Poulter, L, Gitt, MA, Burlingame, AL, Barondes, SH and Leffler, H. (1993) Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase. J Biol Chem 268:26704-26711. [Pubmed]

49. Huflejt, ME, Turck, CW, Lindstedt, R, Barondes, SH and Leffler, H. (1993) L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I. J Biol Chem 268:26712-26718. [Pubmed]

50. Kassarjian, A, Schellenberger, V and Turck, CW. (1993) Screening of synthetic peptide libraries with radiolabeled acceptor molecules. Pept Res 6:129-133. [Pubmed]

51. Lahesmaa, R, Shanafelt, M-C, Allsup, A, Soderberg, C, Anzola, J, Turck, CW, Steinmann, L and Peltz, G. (1993) Preferential usage of T-cell antigen receptor-V region gene segment V-beta-5.1 by Borrelia-burgdorferi antigen-specific T-cell clones isolated from a patient with lyme disease. J Immunol 150:4125-4135. [Pubmed]

52. Oda, Y, Herrmann, J, Gitt, MA, Turck, CW, Burlingame, AL, Barondes, SH and Leffler, H. (1993) Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain. J Biol Chem 268: 5929-5939. [Pubmed]

53. Schellenberger, V, Turck, CW, Hedstrom, L and Rutter, WJ. (1993) Mapping the S'-subsites of serine proteases using acyl transfer to mixtures of peptide nucleophiles. Biochem 32:4349-4353. [Pubmed]

54. Sharp, D, Blinderman, L, Combs, KA, Kienzle, B, Ricci, B, Wager-Smith, K, Gil, CM, Turck, CW, Bouma, M-E, Rader, DJ, Aggerbeck, LP, Gregg, RE, Gordon, DA and Wetterau, JR. (1993) Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature 365:65-69. [Pubmed]

55. Tsirka, SE, Turck, CW and Coffino, P. (1993) Multiple active conformers of mouse ornithine decarboxylase. Biochem J 293:289-295. [Pubmed]

56. Tsutsumi, A, Kubo, M, Fujii, H, Freire-Moar, J, Turck, CW and Ransom, JT. (1993) Regulation of protein kinase C isoform proteins in phorbol ester-stimulated Jurkat T lymphoma cells. J Immunol 150:1746-1754. [Pubmed]

57. Turck, CW. (1993) Multiple peptide synthesis and applications. ABRF News 4:17-19. [ABRF News]

58. Wang, Z-E, Reiner, SL, Hatam, F, Heinzel, FP, Bouvier, J, Turck, CW and Locksley, RM. (1993) Targeted activation of CD8 cells and infection of b2-microglobulin-deficient mice fail to confirm a primary protective role for CD8 cells in experimental Leishmaniasis. J Immunol 151:2077-2086. [Pubmed]

59. Wershil, BK, Turck, CW, Sreedharan, SP, Yang, J, An, S, Galli, SJ and Goetzl, EJ. (1993) Variants of vasoactive intestinal peptide in mouse mast cells and rat basophilic leukemia cells. Cell Immunol 151:369-378. [Pubmed]

60. Barja, P, Alavi-Nassab, A, Turck, CW and Freire-Moar, J. (1994) Inhibition of T cell activation by protein kinase C pseudosubstrates. Cell Immunol 153:28-38. [Pubmed]

61. Gerszten, RE, Chen, J, Ishii, M, Ishii, K, Wang, L, Nanevicz, T, Turck, CW, Vu, T-KH and Coughlin, S.R. (1994) Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface. Nature 368:648-651. [Pubmed]

62. Goetzl, EJ, Patel, DR, Kishiyama, JL, Smoll, AC, Turck, CW, Law, NM, Rosenzweig, SA and Sreedharan, SP. (1994) Specific recognition of the human neuroendocrine receptor for vasoactive intestinal peptide by anti-peptide antibodies. Mol Cell Neurosci 5:145-152. [Pubmed]

63. Hahm, K, Ernst, P, Lo, K, Kim, GS, Turck, CW and Smale, ST. (1994) The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene. Mol Cell Biol 14:7111-7123. [Pubmed]

64. Kavanaugh, WM, Turck, CW, Klippel, A and Williams, LT. (1994) Tyrosine 508 of the 85-kilodalton subunit of phosphatidylinositol 3-kinase is phosphorylated by the platelet-derived growth factor receptor. Biochem 33:11046-11050. [Pubmed]

65. Kim, J, Namchuk, M, Bugawan, T, Fu, Q, Jaffe, M, Shi, Y, Aanstoot, H-J, Turck, CW, Erlich, H, Lennon, V and Baekkeskov, S. (1994) Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish Stiff-Man Syndrome from insulin-dependent Diabetes Mellitus. J Exp Med 180: 595-606. [Pubmed]

66. Lee, TH, Turck, CW and Kirschner, MW. (1994) Inhibition of CDC2 activation by INH/PP2A. Mol Biol Cell 5:323-338. [Pubmed]

67. Mathews, II, Padmanabhan, KP, Ganesh, V, Tulinsky, A, Ishii, M, Chen, J, Turck, CW, Coughlin, SR and Fenton II, JW. (1994) Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochem 33:3266-3279. [Pubmed]

68. Mujeeb, A, Bishop, K, Peterlin, BM, Turck, CW, Parslow, TG and James, TL. (1994) NMR structure of a biologically active peptide containing the RNA-binding domain of human immunodeficiency virus type 1 Tat. Proc Natl Acad Sci USA 91:8248-8252. [Pubmed]

69. Rottapel, R, Turck, CW, Casteran, N, Liu, X, Birnbaum, D, Pawson, T and Dubreuil, P. (1994) Substrate specificities and identification of a putative binding site for PI3K in the carboxy tail of the murine Flt3 receptor tyrosine kinase. Oncogene 9:1755-1765. [Pubmed]

70. Schellenberger, V, Turck, CW and Rutter, WJ. (1994) Role of the S' subsites in serine protease catalysis-active-site mapping of rat chymotrypsin, rat trypsin, alpha-lytic protease, and cercarial protease from Schistosoma-Mansoni. Biochemistry 33:4251-4257. [Pubmed]

71. Truitt, KE, Mills, GB, Turck, CW and Imboden, JB. (1994) SH2-dependent association of phosphatidylinositol 3' kinase 85-kDa regulatory subunit with the interleukin-2 receptor beta chain. J Biol Chem 269:5937-5943. [Pubmed]

72. Tsu, CA, Perona, JJ, Schellenberger, V, Turck, CW and Craik, CS. (1994) The substrate specificity of Uca pugilator collagenolytic serine protease 1 correlates with the bovine type I collagen cleavage sites. J Biol Chem 269:19565-19572. [Pubmed]

73.Turck, CW. (1994) Radioactive screening of synthetic peptide libraries. Methods 6: 396-400. [Elsevier]

74. Turck, CW and Edenson, SP. (1994) Mapping of tyrosine kinase autophosphorylation sites with synthetic peptide substrates. Pept Res 7:140-145.[Pubmed]

75. Chen, J, Bernstein, HS, Chen, M, Wang, L, Ishii, M, Turck, CW and Coughlin, SR. (1995) Tethered ligand library for discovery of peptide agonists. J Biol Chem 270:23398-23401. [Pubmed]

76. Eide, BL, Turck, CW and Escobedo, JA. (1995) Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK. Mol Cell Biol 15:2819-2827. [Pubmed]

77. Frigeri, A, Gropper, MA, Turck, CW and Verkman, AS. (1995) Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes. Proc Natl Acad Sci 92:4328-4331. [Pubmed]

78. Huang, LW, Turck, CW, Rao, P and Peters, KG. (1995) GRB2 and SH PTP2   potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase. Oncogene 11:2097 2103. [Pubmed]

79. Ishii, K, Gerszten, R, Zheng, YW, Welsh, JB, Turck, CW and Coughlin, SR. (1995) Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate. J Biol Chem 270:16435 16440. [Pubmed]

80. Jackman, JK, Motto, DG, Sun, Q, Tanemoto, M, Turck, CW, Peltz, GA, Koretzky, GA and Findell, PR. (1995) Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells. J Biol Chem 270:7029-7032. [Pubmed]

81. Kavanaugh, WM, Turck, CW and Williams, LT. (1995) PTB domain binding to signaling proteins through phosphotyrosine in a unique sequence motif. Science 268:1177-1179. [Pubmed]

82. Kellogg, DR, Kikuchi, A, Fujii-Nakata, T, Turck, CW and Murray, AW. (1995) Members of the NAP/SET family of proteins interact specifically with B-type cyclins. J Cell Biol 130:661-673. [Pubmed]

83. Kuroki, K, Eng, F, Ishikawa, T, Turck, CW, Harada, F and Ganem, D. (1995) gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of carboxypeptidase gene family. J Biol Chem 270:15022 15028. [Pubmed]

84. Maeda, T, Devens, BH, Fukuse, S, Turck, CW and Webb, DR. (1995) Evidence for a calcium regulated, bidirectional intronic promotor in the murine TCR Va1 gene. Int Immunol 7:1339-1351. [Pubmed]

85. Nanevicz, T, Ishii, M, Wang, L, Chen, M, Chen, J, Turck, CW, Cohen, FE and Coughlin, SR. (1995) Mechanism of thrombin receptor agonist specificity. J Biol Chem 270:21619-21625. [Pubmed]

86. Bachl, J, Turck, CW and Wabl, M. (1996) Translatable immunoglobulin germ-line transcript. Eur J Immunol 26:870-874. [Pubmed]

87. Ernst, P, Hahm, K, Trinh, L, Davis, JN, Roussel, MF, Turck, CW and Smale, ST. (1996) A potential role for Elf-1 in terminal transferase gene regulation. Mol Cell Biol 16:6121-6131. [Pubmed]

88. Fournier, E, Rosnet, O, Marchetto, S, Turck, CW, Rottapel, R, Pelicci, PG, Birnbaum, D and Borg, JP. (1996) Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase. J Biol Chem 271:12956-12960. [Pubmed]

89. Hammonds Odie, LP, Jackson, TR, Profit, AA, Blader, IJ, Turck, CW, Prestwich, GD and Theibert, AB. (1996) Identification and cloning of centaurin {alpha}. A novel phosphatidylinositol 3,4,5 trisphosphate binding protein from rat brain. J Biol Chem 271:18859-18868. [Pubmed]

90. Ingham, RJ, Krebs, DL, Barbazuk, SM, Turck, CW, Hirai, H, Matsuda, M and Gold, MR. (1996) B cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteins. J Biol Chem 271:32306-32314. [Pubmed]

91. Lee, LC, Hunter, JJ, Mujeeb, A, Turck, CW and Parslow, TG. (1996) Evidence for alpha-helical conformation of an essential N-terminal region in the human Bcl2 protein. J Biol Chem 271:23284-23288. [Pubmed]

92. Park, H, Wahl, MI, Afar, DEH, Turck, CW, Rawlings, D, Tam, C, Scharenberg, AM, Kinet, J-P and Witte, ON. (1996) Regulation of Btk function by a major autophosphorylation site within the SH3 domain. Immunity 4:515-525. [Pubmed]

93. Shum, L, Turck, CW and Derynck, R. (1996) Cysteines 153 and 154 of transmembrane transforming growth factor-alpha are palmitoylated and mediate cytoplasmic protein association. J Biol Chem 271:28502 28508. [Pubmed]

94. Wang, L-Y, Edenson, SP, Yu, Y-L, Senderowicz, L and Turck, CW. (1996) A natural kinase-deficient variant of fibroblast growth factor receptor 1. Biochemistry 35: 10134-10142. [Pubmed]

95. Beals, CR, Sheridan, CM, Turck, CW, Gardner, P and Crabtree, GR. (1997) Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science 275:1930-1933. [Pubmed]

96. Bringaud, F, Stripecke, R, Frech, GC, Freedland, S, Turck, CW, Byrne, EM and Simpson, L. (1997) Mitochondrial glutamate dehydrogenase from leishmania tarentolae is a guide RNA-binding protein. Mol Cell Biol 17:3915-3923. [Pubmed]

97. Fowell, DJ, Magram, J, Turck, CW, Killeen, N and Locksley, RM. (1997) Impaired Th2 subset development in the absence of CD4. Immunity 6:559-569. [Pubmed]

98. Lawler, S, Feng, XH, Chen, RH, Maruoka, EM, Turck, CW, Griswold Prenner, I and Derynk, R. (1997) The type II transforming growth factor beta receptor autophosphorylates not only on serine and threonine but also on tyrosine residues. J Biol Chem 272:14850-14859. [Pubmed]

99. Medzihradszky, KF, Phillips, NJ, Senderowicz, L, Wang, P and Turck, CW. (1997) Synthesis and characteriztion of histidine-phosphorylated peptides. Protein Sci 6:1405-1411. [Pubmed]

100.Min, HS, Turck, CW, Nikolic, JM and Black, DL. (1997) A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer. Genes Dev 11:1023 1036. [Pubmed]

101.Musci, MA, Hendricks Taylor, LR, Motto, DG, Paskind, M, Kamens, J, Turck, CW and Koretzky, GA. (1997) Molecular cloning of SLAP 130, an SLP 76 associated substrate of the cell antigen receptor stimulated protein tyrosine kinases. J Biol Chem 272:11674-11677. [Pubmed]

102.Namchuk, M, Lindsay, L, Turck, CW, Kanaani, J and Baekkeskov, S. (1997) Phosphorylation of serine residues 3,6,10, and 13 distinguishes membrane anchored from soluble glutamic acid decarboxylase 65 and is restricted to glutamic acid decarboxylase 65a. J Biol Chem 272:1548-1557. [Pubmed]

103.Senderowicz, L, Wang, J-X, Wang, L-Y, Yoshizawa, S, Kavanaugh, WM and Turck, CW. (1997) Phosphohistidine cannot replace phosphotyrosine in high-affinity binding to phosphotyrosine binding or src homology 2 domains. Biochem 36:10538-10544. [Pubmed]

104. Turck, CW. (1997) High-performance liquid chromatography on-line derivative spectroscopy for the characterization of peptides with aromatic amino acid residues. Methods Mol Biol 64:109-117. [Pubmed]

105. Fu, C, Turck, CW, Kurosaki, T and Chan, AC. (1998) BLNK: a central linker protein in B cell activation. Immunity 9:93-103. [Pubmed]

106. Jones, SL, Wang, J, Turck, CW and Brown, EJ. (1998) A role for the actin-bundling protein L-plastin in the regulation of leukocyte integrin function. Proc Natl Acad Sci 95:9331-9336. [Pubmed]

107.Nguyen, JT, Turck, CW, Cohen, FE, Zuckermann, RN and Lim, WA. (1998) Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science 282:2088-2092. [Pubmed]

108. Reiner, SL, Fowell, DJ, Moskowitz, NH, Swier, K, Brown, DR, Brown, CR, Turck, CW, Scott, PA, Killeen, N and Locksley, RM. (1998) Control of Leishmania major by a monoclonal alpha beta T cell repertoire. J Immunol 160:884-889. [Pubmed]

109.Bloom, D, Jabrane-Ferrat, N, Zeng, L, Wu, A, Lo, D, Turck, CW, An, S and Goetzl, EJ. (1999) Prostaglandin E2 enhancement of interferon-gamma production by antigen-stimulated type 1 helper T cells. Cell Immunol 194:21-27. [Pubmed]

110.Chou, M-Y, Rooke, N, Turck, CW and Black, DL. (1999) hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. Mol Cell Biol 19:69-77. [Pubmed]

111.Jabrane-Ferrat, N, Bloom, D, Wu, A, Li, L, Lo, D, Sreedharan, SP, Turck, CW and Goetzl, EJ. (1999) Enhancement by vasoactive intestinal peptide of gamma-interferon production by antigen-stimulated type 1 helper T cells. FASEB J 13:347-353. [Pubmed]

112.Jonosono, M, Fang, KC, Keith, FM, Turck, CW, Blanc, PD, Hall, TS, Fukano, AK,

Rifkin, CJ, Gold, WM, Webb, WR, Edinburgh, KJ, Finkbeiner, WE and Golden, JA. (1999) Measurement of fibroblast proliferative activity in bronchoalveolar lavage fluid in the analysis of Obliterative Bronchiolitis among lung transplant recipients. J Heart Lung Transplant 18:972-985. [Pubmed]

113.Lasker, M, Bui, CD, Besant, PG, Sugawara, K, Thai, P, Medzihradszky, G and Turck, CW. (1999) Protein histidine phosphorylation: increased stability of thiophosphohistidine. Protein Sci 8:2177-2185. [Pubmed]

114.Pingel, S, Launois, P, Fowell, DJ, Turck, CW, Southwood, S, Sette, A, Glaichenhaus, N, Louis, JA and Locksley, RM. (1999) Altered Ligands Reveal Limited Plasticity in the T Cell Response to a Pathogenic Epitope. J Exp Med 189:1111-1120. [Pubmed]

115.Pollock, N, de Hostos, EL, Turck, CW and Vale, RD. (1999) Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium. J Cell Biol 147:493-505. [Pubmed]

116.Straight, AF, Shou, W, Dowd, GJ, Turck, CW, Deshaies, RJ, Johnson, AD and Moazed, D. (1999) Net1, a Sir2-associated nucleolar protein required for rDNA silencing and nucleolar integrity. Cell 97:245-256. [Pubmed]

117.Bass, J, Turck, CW, Rouard, M and Steiner, DF. (2000) Furin-mediated processing in the early secretory pathway: Sequential cleavage and degradation of misfolded insulin receptors. Proc Natl Acad Sci 97:11905-11909. [Pubmed]

118.Besant, PG, Lasker, M, Bui, CD and Turck, CW. (2000) Phosphohistidine analysis using reversed phase thin layer chromatography. Anal Biochem 282:149-153. [Pubmed]

119.Dell, KR, Turck, CW and Vale, RD. (2000) Mitotic phosphorylation of the dynein light intermediate chain is mediated by cdc2 kinase. Traffic 1:38-44. [Pubmed]

120.Dyall, SD, Koehler, CM, Delgadillo-Correa, MG, Bradley, PJ, Plümper, E, Leuenberger, D, Turck, CW and Johnson, PJ. (2000) Presence of a member of the mitochondrial carrier family in hydrogenosomes: Conservation of membrane-targeting pathways between hydrogenosomes and mitochondria. Mol Cell Biol 20:2488-2497. [Pubmed]

121.Goetzl, EJ, Lee, H, Azuma, T, Stossel, TP, Turck, CW and Karliner, JS. (2000) Gelsolin binding and cellular presentation of lysophosphatidic acid. J Biol Chem 275:14573-14578. [Pubmed]

122.Ko, BCB, Turck, CW, Lee, KWY, Yang, Y and Chung, SSM. (2000) Purification, identification, and characterization of an osmotic response element binding protein. Biochem Biophys Res Commun 270:52-61. [Pubmed]

123.Markovtsov, V, Nikolic, JM, Goldman, JA, Turck, CW, Chou, M-Y and Black, DL. (2000)
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