EE 416 Fundamentals of Biomedical Engineering Spring 2006/07
Fundamentals of Biomedical Engineering
Wednesday, 10:40 (DZ-13)
Friday 9:40 (DZ-13)
Instructor: Nevzat G. Gençer,
There will be a new set of notes for each new subject, and they will be available before we start discussing the subject in class. Make sure that you have the notes in the class with you.
R. Plonsey and D. G. Fleming, "Bioelectric Phenomena," McGraw-Hill Book Company
Ramesh M. Gulrajani, "Bioelectricity and Biomagnetism," John Wiley and Sons, NY, 1998
Robert Pronsey and Roger Barr, "Bioelectricity - a quantitative approach," Kluwer Academic/Plenum Publishers, NY., 2000.
J. Malmivuo and R. Plonsey, Bioelectromagnetism," Oxfor University Press. Also available online at: http://butler.cc.tut.fi/~malmivuo/bem/bembook/index.htm
John G. Webster (Ed.), "Medical Instrumentation, application and design," Houghton Mifflin Company, Boston.
B.H. Brown, R.H. Smallwood, D.C. Barber, et.al., "Medical Physics and Biomedical Engineering," Institute of Physics, ISBN 0-7503-0368-9.
J.D. Enderle, S.M. Blanchard, J.D. Bronzino, "Introduction to Biomedical Engineering," Academic Press, ISBN 0-12-238660.
Vander, Sherman, Luciano, "Human Physiology," McGraw Hill.
Ferit Pehlivan, "Biyofizik," Ankara Universitesi Tip Fakultesi, Ankara.
Albert M. Cook and John G. Webster (Eds.), "Therapeutic Medical Devices - application and design," Prentice Hall, NJ.
Ramon Pallas-Areny and John G. Webster, "Sensors and Signal Conditioning," John Wiley and Sons, NY (Reference book for the laboratory).
Resting electrical properties of cells and electrical equivalent model.
Action potential properties
Action potential propagation and external fields
Synaptic transmission and neuromascular junction
Electroneurogram (ENG) and electromyogram (EMG)
Electrical activation of the heart: anatomy and function of the heart, electrical behavior of cardiac cells, ventricular activation.
Body surface potentials and dipole theory of electrocardiogram (ECG)
Electroencephalography (EEG): introduction to the anatomy and function of the brain, cerebrum, cerebellum, brain stem, cerebral cortex, electrical potential from the brain, resting rhythms of the brain, clinical EEG
Biopotential electrodes: electrode circuit models, electrode- skin interface and motion artifact.
Biopotential amplifiers: specific requirements, frequently encountered problems, common mode and other interference reduction circuits. Patient safety, isolation, grounding and shielding in biomedical instrumentation.
Therapeutic and prosthetic devices (pacemaker, defibrillator, respirator, intra-aortic balloon pump, etc.)
Simple mechanical model of ventilation.
Measurement of respiratory volumes and flow.
2 Midterms 20% each
Final Exam 30%
Term Project 10%
Laboratory: There will be 9 experiments.