Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal




Скачать 114.28 Kb.
НазваниеBiology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal
страница1/3
Дата06.09.2012
Размер114.28 Kb.
ТипДокументы
  1   2   3



SEMESTER I

Hrs

6

Credit

5

Code

08 PBI 1401

Marks

75

CORE COURSE – I

BIOLOGICAL SYSTEMS

UNIT-I


Biology of Cells: Prokaryotic and Eukaryotic cells - E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal cells, Principles of Membrane organization, Membrane proteins, Cell transport, Cell division - mitosis, meiosis- cell cycle; Enzymes- classification, structure, Mechanism of action.


UNIT-II


Cell Energetics and respiration: Energy - life's driving force; energy capture – photosynthesis; role of ATP in energy cycle - Glycolysis, TCA cycle, Oxidative phosphorylation; Fats and protein as alternate energy sources, Key biomolecules - lipids, polysaccharides, proteins, nucleic acids.


UNIT-III


Chromosome structure in Prokaryotes and Eukaryotes, Structures of DNA - Watson and Crick model, Different conformations, Replication; RNA secondary structure; Central dogma of molecular biology-Transcription, Post – transcriptional modifications, codon and anticodon concepts, Translation and Post–translational modifications; Mutation-Types, Molecular mechanism- DNA repair mechanism- Gene regulation- operon concept - lac, trp.


UNIT IV


Basics of recombinant DNA technology - Introduction to cloning, gene selection, restriction enzymes-a brief account; cloning vectors – plasmid, phage vectors, cosmids, shuttle vectors; DNA transformation; methods of clone selection and screening. Hybridization techniques-Southern-Northern-Western blots analysis and their applications.


UNIT-V


DNA sequencing- Maxam-Gilbert, Sanger methods, automated DNA sequencing. PCR, RFLP and RAPD techniques, bio-chips and DNA finger printing, Applications of recombinant DNA technology - commercial aspects of recombinant proteins.


Text Books :


  1. Freifelder D. Molecular Biology, Jones and Bartlett Publishers Inc. 1987. Lehninger A.L., Principles of Biochemistry, CBS Publishers and Distributors, New Delhi, 1984.

  2. Berg, J. M. , J.L. Tymoczko and L. Stryer, Biochemistry, 5th Edition W.H. Freeman, 2002.


Reference Books :


  1. Benjamin Lewin, Genes VIII, Pearson - Prentice Hall International Edition, New Delhi. 2004.

  2. Watson, J.D., et al., Recombinant DNA, 2nd ed. Scientific American Books, New York, 1992.

  3. Winnacker E. L. From Genes to Clones, VCH Weinhem, Germany, 1987.

  4. Prokop, Ales, Bajpai, Rakesh K., and Ho, Chester S., Recombinant DNA Technology and Applications, McGraw-Hill, New York, 1991.



SEMESTER I

Hrs

6

Credit

5

Code

08 PBI 1402

Marks

75


CORE COURSE – II

PROGRAMMING IN C

Unit I


Computer Introduction: Overview and functions of a computer System. Input and output devices. Storage devices: Hard Disk, Diskette, Magnetic Tape, CD-ROM, DVD, Main Board: Chips, Ports, Expansion Slots. Memory: Register, buffer, RAM / ROM, Types of Computer on usage and capability.


Unit II


Types of Software – operating systems, application program – tools, packages , Networks – LAN, WAN, MAN – Routers, Hubs. Concepts of flowchart, algorithm – Programming Techniques.


Unit III


C’ programming: Data types, operators and expressions, Hierarchy of operators Declaring Variable and constants, Control statements including decision (if, if-else), loops (while, do-while, for), branching (switch, break, continue), Iterative statements, Functions – Simple, recursive functions, library functions – arguments.


Unit IV


Arrays – one dimension, two dimension, string and numeric, Pointers, array of pointers, Pointer to pointer, File Operations in C – read, write, append – Sequential and random files. Opening and closing of files for data.


Unit V


Structures, unions, storage classes, dynamic memory allocation, macros and preprocessor directives, command line arguments.


Reference Books:


  1. Gary Bronson J., A First book of ANSI C, 3rd edition, Thomson Asia pvt. Ltd., Bangalore, 2001.

  2. Gottfried, B. S., Programming With C, Tata Mc Graw Hill

  3. Lorry Wall, Tom Cheristiansan, Joe Orwant. Programming Perl, Shroff Publishers, Mumbai, 2005

  4. Tisdall, J., Beginning Perl for bioinformatics, Shroff publishing, Mumbai, 2006



SEMESTER I

Hrs

6

Credit

5

Code

08 PBI 1403P

Marks

60


CORE COURSE – III


C Programming – Lab


1. C Basic Input / Output Functions

2. Arrays Concepts

3. Example for Structure

4. Sample program for Pointers

5. Illustration of Conditional Statements

6. Explaining Looping Statements

7. Functions – recursive, library functions

8. Dynamic memory Allocation

9. Data Structure operations like stacks and queues

10. File Operations including read, write and appending records


SEMESTER I

Hrs

6

Credit

4

Code

08 PBI 1404

Marks

75


CORE COURSE – IV

BIOSTATISTICAL AND MATHEMATICAL TECHNIQUES


UNIT I


BIOSTATISTICS – Introduction – Applications, Collection of Data: Sampling techniques, Graphical and diagrammatic representation.

CENTRAL TENDENCY – Arithmetic Mean, Geometric Mean, Harmonic Mean, Median, Mode

DISPERSION – Importance, range, Mean Deviation, Variance, Standard Deviation


UNIT II


CORRELATION – types & measures, Karl Pearson, Scatter Diagram, Rank Correlation, Correlation for bivariate frequency distribution, REGRESSION - types, measures, Testing of hypothesis, ANOVA – One way, Two way, STUDENT ‘t’ tests for mean and difference of mean, CHI SQUARE distribution: independent of attributes, goodness of fit.


UNIT III


PROBABILITY – Basic Laws: Events, Sample Space, Addition Rule, multiplication Rule, Random Variable, Probability Distribution, NORMAL Distribution, BINOMIAL Distribution, Poisson distribution, Introduction to Hidden Markov model


UNIT IV


CALCULUS – Basics, Differentiation of algebraic functions, Trigonometric functions, Integrations – simple problems, properties of definite integrals , Uses of table of Integrals, Numerical differentiations – Euler’s method, R-K second order method, Numerical integration: Trapezoidal and Simpson 1/3 rule.


UNIT V


MATRIX – Types, Inverse, Algebra, Simultaneous Equations, Determinant, Eigen Values , Rank of a matrix. VECTORS – Operations, Scalar, Vector Product, Vector Calculus, Scalar Triple Product, Divergence, Curl of Vector.


Reference Books:


  1. Veer Bala Restogi, Fundamental of Biostatistics, Ane Books, New Delhi, 2006

  2. Jorden D. W. , Smith P., Mathematical Techniques, 3 rd Edition, Oxford University Press, New Delhi, 2004

  3. Pillai RSM, Bagavathi,V., Chand .S “Statistics”

  4. Ronald N.Forthofer Einsun, “Introduction to Biostatistics” Elsevier, 2006



SEMESTER I

Hrs

6

Credit

4

Code

08 PBI 1501

Marks

75


CORE BASED ELECTIVE COURSE – I


BIOPHYSICS AND STEREOCHEMISTRY

UNIT-I


Parameters to describe a structure: bond angle, bond length and bond strength. Levels of structure description: primary, secondary, tertiary and quarternary structures. Forces deciding the molecular structures: inter and intramolecular forces – hydrogen bonding, hydrophobic interactions and water structure, ionic interactions, disulphide bonds.


UNIT-II


Forces driving the molecular structures: Conformation, potential energy calculations, potential well, L-J curve, time scales and energy criteria, conformational principles, conformational space. Types of movements: vibrational, rotational, torsion angles; Conformational analysis, calculation of surface areas, Volumes and radius of biomolecules.


UNIT-III


Nucleic acids - structural characteristics of nucleic acids – geometry of glycosidic bond, rotational isomers, sugar puckering; forces stabilizing the structures - base pairing, base stacking. Tertiary structure of nucleic acids; chemical bonds in biomolecules – hydrogen bond, peptide bond, phosphate bond.


UNIT-IV


Stereochemistry: Principles - Chirality, Symmetry in organic compounds, Molecular isomerism, polypeptide chain geometries - Ramachandran plot, observed values for rotation angles, prediction of protein structure.


UNIT-V


Application of sterochemical principles: Conformation of open chain compounds, chiral compounds, Macromolecular stereochemistry, Determination of relative and absolute configuration.


Reference Books


  1. Cantor, Q. R., and P.R.Schimmel, Biophysical Chemistry Part - 1, 2, & 3. W.H. Freeman & Co., San Francisco, 1980.

  2. Branden, C. and J. Tooze, Introduction to Protein Structure, Garland Publishing Inc., New York, 1991.

  3. Glaser, R. Biophysics, Springer, 2000.

  4. Ernest. L. Eliel et al., Sterochemistry of Organic Compounds. John Wiley & Sons, 1994.

  5. Kalsi, P.S., Sterochemistry - Conformation & Mechanism, New Age International Ltd., 1990.



SEMESTER II

Hrs

6

Credit

5

Code

08 PBI 2405

Marks

75
  1   2   3

Похожие:

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconBiology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconA study in the Conjugation between Mutant E. coli Donor and Recipient Cells

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconStudents studying for Bio U117 Exam 1 should only review the sections «Introduction and terminology», «Basic chemistry», «Cells and membrane transport
...
Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconU nit-2 genetics of prokaryotes and eukaryotic organelles and gene structure & expression

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconTranscription Regulatory Networks in Yeast Cell Cycle

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconChapter 5 Visualizing cells and the csk visible Light microscopy

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconBionems, NanoFluidics, Micro Fuel Cells, mems package and ic

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconProgrammed cell death, or apoptosis, is currently one of the hottest areas of modern biology. It describes the orchestrated collapse of a cell, staging membrane

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconCharacterization of leukotriene D4-induced gene signatures in human endothelial cells

Biology of Cells: Prokaryotic and Eukaryotic cells E. coli and Yeast; Cell organelles and their functions, Differences and similarities in plant and animal iconF ermentation: If oxygen is absent, many cells are still able to use glycolysis to produce atp. Two ways this can be done are through fermentation and anaerobic

Разместите кнопку на своём сайте:
Библиотека


База данных защищена авторским правом ©lib.znate.ru 2014
обратиться к администрации
Библиотека
Главная страница