Scheme of Instruction and Evaluation for M. Pharmacy




Скачать 275.73 Kb.
НазваниеScheme of Instruction and Evaluation for M. Pharmacy
страница2/2
Дата17.10.2012
Размер275.73 Kb.
ТипДокументы
1   2
PARTS OF DISSERTATION/RESEARCH REPORT/ARTICLE

Introduction, Review of Literature, Methodology, Results and Discussion

Ask questions related to: content, continuity, clarify, validity internal consistency and objectivity during writing each of the above parts.

UNIT – V

WRITING FOR GRANTS

Clearly state the question to be addressed; Rationale and importance of the question being address; Emperial and theoretical conceptualization; Presenting pilot study/data; Research proposal of method; Clarity, specificity of method; Clear organization; Outcome of study and its implications; Budgeting; Available infra-structure and recourses and Executive summary


References



  1. 1. APA (1984): Publication Manual of Americal Psychological Association 3rd Ed, Washington.

  2. 2. Cooper, H.M. (1990): Integrating Research: A Guide for Literature Reviews (2nd Edition). California: Sage.

  3. 3. Dunn, F.V & Others.(Ed.) (1984): Disserninating Research: Changing Practice. NY:Sage.



INTELLECTUAL PROPERTY RIGHTS AND REGULATORY AFFAIRS

M PCH.T.1.201 Period/Week: 4

Examination: 70 Nature of Exam: Theory

Sessional: 30 Duration of Exam: 3 hrs


UNIT – I

Patents and Intellectual Property Rights (IPR): definition, scope, objectives, source of patient information, patent processing and application. Patents, copyrights, trademarks, silent features, trade related aspects (TRIPS), international and regional agreements.

UNIT – II

GATT and WTO: GATT – historical, prospectives, objectives, fundamental principles, impact on developing countries. WTO-objectives, scope, functions, structure, status, membership and withdrawal, dispute settlement, impact on globalization, India-tasks & challenges.

UNIT – III

Regulatory Affairs: Indian context – requirements and guidelines of GMP, understanding of drugs and cosmetics act 1940 and rules 1945 with reference to schedule M, U and Y.

UNIT – IV

Related Quality Systems: Objectives and guidelines of USFDA, WHO and ICH. Introduction to ISO series.

UNIT – V

Documentation: Documentation types related to pharmaceutical industry, protocols, harmonizing formulation development for global filings, NDA, ANDA, CTD, dealing with post-approval changes – SUPAC, handling and maintenance including electronic documentation.

Recommended Books:

  1. 1. Guarino RA. New drug approval process, 4th ed., vol 139, Marcel Dekker Inc., New York, 2004.

  2. 2. Willing SH. Good manufacturing practices for pharmaceuticals. 5th ed., vol 109, Marcel Dekker Inc., New York, 2001.

  3. 3. Das P, Das G. Protection of industrial property rights.

  4. 4. Katju SN. Laws and drugs. Law Publishers.

  5. 5. Original Laws published by Government of India.

  6. 6. Hussain. Law of drugs in India.

  7. 7. Websites: www.fda.org ; www.wipo.int , www.ich.org , www.cder.org .





ADVANCES IN PHARMACOLOGY

Subject Code : M.PCOL T 1.202 Sessional : 30

Periods/week : 6 Examination : 70

Nature of Exam: Theory Exam Duration: 3 Hrs

UNIT –I

Receptor Pharmacology

General aspects of receptor pharmacology,structural and functional aspects of receptor s, regulation of receptors,isolation,classification and characterization of receptors.

UNIT – II

Neurotransmission Pharmacology

General aspects and steps involoved in neurotransmission

Neurohumoral transimission in autonomic nervous system.

Neurohumoral transmission in central nervous system

Non-adrenergic non-cholinergic transmission [NANC].

UNIT – III

A detailed study of the mechanism of action, pharmacology of drugs used in

ANS-Parasympathomimetics and lytics, sympathomimetics and lytics, agents acting at neuromuscular junction and ganglia.

CNS- General anaesthetics, sedatives, hypnotics. Drugs used to treat anxiety, depression, psychosis, mania,epilepsy, neurodegenerative deseases, drug dependence and addiction.

CVS- diuretics, anti ischemics, antihypertensives, antiarrythmics, drugs for heart failure and dyslipieiemia.

UNIT – IV

A detailed study of the mechanism of action, pharmacology of drugs used in

Autocoid pharmacology- a study of the mechanisms involved in the

formation, release, pharmacological actions and possible physiological role

of histamine,serotinine,kinins,prostaglandins,opioidautocoids and cyclic

3’ – 5’ AMP. Systemic pharmacology of drugs acting as agonists and antagonists

to the autocoids.

GIT Pharmacology – anti ulcer,prokinetics,antiemetics, antidiarrhoeal and drugs for

constipation and irritable bowel syndrome.

Hormone and hormone antagonists.Anti biotics and chemotherapeutic agents. Analgesics and anti-inflammatory agents.

UNIT – V

FREE RADICAL AND IMMUNO PHARMACOLOGY

Generation of free radicals, role of free radicals in etiopathology of various diseases, protective activity of certain important antioxidants. Cell and biochemical mediators involved in allergy, immunomodulation and inflammation. Classification of hypersensitivity reactions and diseases involved. Therapeutic agents for allergy, asthma, COPD and other immunological diseases with emphasis on immunomodulators.


Recommemded books



  1. 1. Clinical Pharmacology by D.R.Lawrnce and P.N.Bennette

  2. 2. Pharmacology and Pharmacotherapeutics R.S. Satoskar and S.D. Bhandarkar.

  3. 3. The Pharmacology basis of therapeutics. 10th edition by Louis S.Goodman and Altred Gillman

  4. 4. Pharmacology by H.P. Rang and M.A. Dale

  5. 5. Biopharmaceutics and Pharmacokinetics and introduction by E. Notary

  6. 6. Drug Metabolism by Berhard Tests and Peter Jenner.

  7. 7. Principles of Drug action by Goldstein, Aranow and Kolman.

  8. 8. Pharmacokinetics : Regularory Industrial Academic Perspectives, Second Edition, edited by Peter G.Welling and Francis L.S.Tse

  9. 9. The Drug Development Process: Increasing Efficiency and cost Effectiveness, edited by Peter G.Welling, louis Lasagna and Umesh V. Banakar


10. Pharmaceutical Practice , Win field


BIOPHARMACEUTICS AND PHARMACOKINETICS

Subject Code : M.PCOL.T.1.203 Sessional : 30

Period / Week: 4 Examinations : 70

Nature of Exam: Theory Duration of Exam: 3 hrs

UNIT -1

Bioavailability and Bioquiovalence: Objectives, bioavailability & variations, measurements of bioavailability, enhancing bioavailability, concepts of equivalents, official bioequivalence protocols & therapeutic equivalence.

UNIT -2

Drug Absorption: General consideration, absorption / drug transport mechanisms, role factors affecting absorption, absorption of drug non-peroral routes, methods of determining absorption-in-vitro, in-situ, and in-vivo methods.

Drug Distribution: Factors affecting, protein & tissue binding, kinetics, determination of rate constants & different plots (direct, Scatchard, & reciprocal).

UNIT -3

Pharmacokinetcs: Parameters & determination, pharmacokinetic models – one compartment, multi compartment in IV bolus, IV infusion & extra vascular, drug & metabolites levels in blood, urine and other

biological fluids. Integration of kinetics.

Application of pharmacokinetics in new drug development, design of dosage forms and novel drug delivery systems.

UNIT - 4

Drug Disposition and Excretion: Biotransformation, factors affecting biotrasformation, Phase I & Phase-II reactions.

Clearance: Concept, renal, non-renal clearance, mechanism, determination, % drug metabolized, different volume of distribution.

UNIT – 5

Pharmacokinetics of Multiple Dosing: Various terminology, determination, adjustment of dosage in renal & hepatic impairment, individualization of therapy, therapeutic drug monitoring.

Non-linear kinetics: Cause of non-linearity, estimation of various parameters, bioavailability of drugs that follow non-linear kinetics. Chronopharmacokinetics & pharmacokinetics of elderly and infants.

Recommended books

1. Biopharmaceutics and Clinical Pharmacokinetics, Mile Gibaldi, Lea and Febriger, Philadelphia.

2. Current concepts in Pharmaceutical Sciences, Swarbrick, Lea and Febriger, Philadelphia.

3. Theory & Practice of Industrial Pharmacy, L.Lachman, Varghese Publ, Bombay.

4. Clinical Pharmacokinetics, Rowland and Tozer, Lea and Febriger, Philadelphia.

5. Biopharmaceutics and Clinical Pharmacokinetics, Niazi, Prentice Hall, London.

6. Remingtons Pharmaceutical Sciences, Mack & Co.

7. Biopharmaceutics & Clinical Pharmacokinetics, DM Brahmankar, Vallabh, Delhi.

8. C.V.S.Subrahmanyam, Textbook of Biopharmaceutics and Pharmacokinetics, 2009, Vallabh Prakashan, Delhi.




PHARMACOLOGY & PHARMACO THERAPEUTICS

Subject Code : M.PCOL T.1.204 Sessional : 30

Periods/Week : 4 Examination : 70

Nature of Exam : Theory Exam Duration : 3 Hrs

UNIT –I

Principles of Pharmacokinetics.



  1. A. Revision of Basic concepts.

  2. B. Clinical Pharmacokinetics.

    1. 1. Dose – response in man

    2. 2. Influence of renal and hepatic disease on Pharmacokinetics

    3. 3. Therapeutics drug monitoring

    4. 4. Population Pharmacokinetics.



UNIT – II

Basics in clinical pharmacology

Clinical trials of drugs,design of clinical trials

Therapeutic drug monitoring and critieria for TDM.

Adverse Drug Reactions, Drug Interactions and ADR monitoring.

UNIT – III

Pathophysiology and drug therapy of the following disorders.

Schizophrenia, anxiety, depression, epilepsy, Parkinson’s Alzheimer’s diseases Migraine hypertension, angina pectoris, arrhythmias, atherosclerosis, myocardial infraction, TB, leprosy, leukemia, solid tumors, lymphomas, psoriasis, respiratory, urinary , g.i. tract infections, endocarditic, fungal and HIV infection, rheumatoid arthritis, glaucoma, menstrual disorders, menopause.

UNIT – IV

Drug therapy and Pharmacokinetics in

  1. a. Geriatrics

  2. b. Pediatrics

  3. c. Pregnancy & Lactation.



UNIT - V

Pharmacogenetics: Historical aspects of pharmacogenetics, biomarkers, inter-racial and individual variability in drugs metabolism., receptors .Role of drug transporters, interethnic differences, clinical view points and future perspectives, stem cell – a new therapeutic approach. Gene therapy, Pharmacovigilance concepts and its impact.


Recommended Books



  1. 1. Biopharmaceutics and Pharmacokinetics, Venkateshwarlu

  2. 2. Clinical Pharmacy and therapeutics , Herfindal

  3. 3. Drug Disposition and Pharmacokinetics , H.Curry

  4. 4. Pharmacokinetics ,Milo Gibaldi

  5. 5. Managing clinical Drug development , Cocchetto

  6. 6. Pharmacogenomics , Kalow

  7. 7. Durg discovery and development, Rang

  8. 8. Basic Statistics and Pharmaceutical Statistical applications , Muth

  9. 9. Pharmacokinetics for the Pharmaceutical Scientist , Wagner

  10. 10. W.H.O Publications ,Technical Report Series.

  11. 11. Clinical Pharmacology by D.R.Lawrnce and P.N.Bennette



ADVANCES IN PHARMACOLOGY PRACTICALS

Subject Code : M.PCOL P.1.205 Sessional : 30

Periods/week : 6 Examination : 70

Nature of Exam: Practicals Exam Duration: 6 Hrs

List of Experiments.

Minimum 8 experiments shall be conducted.

  1. 1. Experiments for studying the effects of the more important biogenic agents like histamine, acetylcholine, 5HT, oxytocin and their effect in the presence of antagonist on suitable isolated tissue preparations.

  2. 2. Estimation of PA2 values of various antagonists under suitable isolated tissue preparations.

  3. 3. Experiments on CVS- effect of various drugs on isolated heart preparations on various animal models under normal arrhythmic and hypo dynamic conditions.

  4. 4. Drugs acting on Gastro intestinal tract. To study the drug activity on oesophagal motility.

  5. 5. Monitoring of drug concentrations in saliva/urine/blood.

  6. 6. Action of CNS stimulants and depressants using suitable experimental model.

  7. 7. Evaluation of antidepressant and anti anxiety drugs.

  8. 8. Drug absorption and elimination studies.

  9. 9. Any other experiment based on the topics mentioned in theory,

  10. 10. Virtual and stimulated experiments are permitted.



BIOPHARMACEUTICS AND PHARMACOKINETICS


Subject Code : M.PCOL.P.1.206 Sessional : 30

Period / Week: 6 Examinations : 70

Nature of Exam: Practicals Duration of Exam: 6 hrs


Suggested experiments

1. Comparative dissolution studies on different dosage forms for drugs.

2. Effect of pH / particle size on dissolution studies.

3. Plasma protein binding studies on different drugs.

4. Estimation of pharmacokinetic parameters in urine / serum samples.

5. Estimation of creatinine clearance.

6. Estimation of pharmacokinetic parameters for the given urinary excretion data.

7. Estimation of pharmacokinetic parameters for the given oral absorption data.





ENTREPRENEURSHIP MANAGEMENT

Subject Code : M.PCOL T 1.207 Sessional : 50

Periods/week : 2 Examination : --

Nature of Exam: Tutorials Exam Duration: --

Course Objectives:

  1. • To provide conceptual inputs regarding entrepreneurship management.

  2. • To sensitize and motivate the students towards entrepreneurship management.

  3. • To orient and impart knowledge towards identifying and implementing entrepreneurship opportunities.

  4. • To develop management skills for entrepreneurship management.


UNIT – I: CONCEPTUAL FRAME WORK

  1. - Concept need and process in entrepreneurship development.

  2. - Role of enterprise in national and global economy

  3. - Types of enterprise – Merits and Demerits

  4. - Government policies and schemes for enterprise development

  5. - Institutional support in enterprise development and management


UNIT – II: THE ENTREPRENEUR

  1. - Entrepreneurial motivation – dynamics of motivation.

  2. - Entrepreneurial competency – Concepts.

  3. - Developing Entrepreneurial competencies - requirements and understanding the process of entrepreneurship development, self awareness, interpersonal skills, creativity, assertiveness, achievement, factors affecting entrepreneur'’ role.


UNIT – III: LAUNCHING AND ORGANISING AN ENTERPRISE

  1. - Environment scanning – Information, sources, schemes of assistance, problems.

  2. - Enterprise selection, market assessment, enterprise feasibility study, SWOT Analysis.

  3. - Resource mobilization - finance, technology, raw material, site and manpower.

  4. - Costing and marketing management and quality control.

  5. - Feedback, monitoring and evaluation.


UNIT – IV: GROWTH STRATEGIES AND NETWORKING

  1. - Performance appraisal and assessment

  2. - Profitability and control measures, demands and challenges

  3. - Need for diversification

  4. - Future Growth – Techniques of expansion and diversification, vision strategies

  5. - Concept and dynamics

  6. - Methods, Joint venture, co-ordination and feasibility study


UNIT – V: PREPARING PROJECT PROPOSAL TO START ON NEW ENTERPRISE

- Project work – Feasibility report; Planning, resource mobilization and implementation.

Reference

  1. 1. Akhauri, M.M.P.(1990): Entrepreneurship for Women in India, NIESBUD, New Delhi.

  2. 2. Hisrich, R.D & Brush, C.G.(1996) The Women Entrepreneurs, D.C. Health & Co., Toranto.

  3. 3. Hisrich, R.D. and Peters, M.P. (1995): Entrepreneurship – Starting, Developing and Managing a New Enterprise, Richard D., Inwin, INC, USA.

  4. 4. Meredith, G.G. etal (1982): Practice of Entrepreneurship, ILO, Geneva.

  5. 5. Patel, V.C.(1987): Women Entrepreneurship – Developing New Entrepreneurs, Ahmedabad EDII.
1   2

Похожие:

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of Instruction and Evaluation for M. Pharmacy

Scheme of Instruction and Evaluation for M. Pharmacy icon23. scheme of instruction

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of instruction and examination

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of instruction and examination

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of instruction and examination

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of instruction : Teaching Hours 4 Periods per week

Scheme of Instruction and Evaluation for M. Pharmacy iconIn the News” – October 25 – November 7, 2008 – Drug- and Pharmacy-related News Brought to You by the Pharmacy Library People

Scheme of Instruction and Evaluation for M. Pharmacy iconScheme of examinations for bba (industry integrated) programme w e. f. Session 2009-2010 (Under Public Private Parternership Scheme)

Scheme of Instruction and Evaluation for M. Pharmacy iconSyllabus For the trade of Sheet Metal Worker Under Craftsmen Training Scheme (cts) Apprenticeship Training Scheme (ats)

Scheme of Instruction and Evaluation for M. Pharmacy iconPublished in Turchin P., Grinin L. E., de Munck, V. C. and Korotayev, A. V. (eds.), History & Mathematics: Historical Dynamics and Development of Complex
Кочакова 1995. However, when we try to apply this scheme to the political development of the World System, it becomes evident that...
Разместите кнопку на своём сайте:
Библиотека


База данных защищена авторским правом ©lib.znate.ru 2014
обратиться к администрации
Библиотека
Главная страница