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CURRICULUM VITAE


MATTHEW RYAN WEIR, M.D.

Professor and Director

Division of Nephrology

University of Maryland School of Medicine


Date July 2009

Contact Information


Matthew R. Weir, M.D.

Professor and Director

Division of Nephrology

University of Maryland Medical Center

22 S. Greene Street, Room N3W143

Baltimore, Maryland 21201

Phone: 410.328.5720

Fax: 410.328.5685


Education

1974 B.A. University of Virginia

Charlottesville, Virginia


1978 M.D. University of Virginia

Charlottesville, Virginia


Internship

1978-1979 The Waterbury Hospital and Yale-New Haven Hospital

Yale University School of Medicine

New Haven, CT


Residency

1979-1980 Junior Assistant Resident in Medicine, The Waterbury Hospital and Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT


1980-1981 Senior Assistant Resident in Medicine, The Waterbury Hospital and Yale-New Haven Hospital, Yale University School of Medicine, New Haven, CT


Research Fellowships:

1981-1982 Clinical Nephrology Fellow, Harvard Medical School and The Brigham and Women's Hospital, Boston, MA


1982-1983 Laboratory of Immunogenetics and Transplantation, Renal Division, Harvard Medical School and The Brigham and Women's Hospital, Boston, MA


POSTGRADUATE CLINICAL EXPERIENCE


1981-1983 General Practice Clinic

The Brigham and Women's Hospital

Boston MA


1981-1983 Medical Consultant

Parker Hill Hospital

Boston, MA


1981-1983 Medical Consultant, Intensive Care Unit

Marlborough Hospital

Marlborough, MA


1983-Present Attending Physician

University of Maryland Hospital,

Baltimore, MD

LICENSURE AND CERTIFICATION



1979 Diplomate of the National Board of Medical Examiners

1980 Connecticut License Registration

1981 Massachusetts License Registration

1981 Diplomate of the American Board of Internal Medicine

1983 Maryland License Registration (#D29710)

1984 Diplomate of the American Board of Internal Medicine for the Subspecialty of Nephrology


MAJOR RESEARCH INTERESTS


▪ Immunobiology of tolerance in allograft transplantation

▪ Hypertensive nephropathy in blacks

▪ Hypertension - Impact of antihypertensive agents on renal hemodynamics, end-organ protection, and modulation of renal-adrenal responses

▪ The influence of dietary sodium on insulin sensitivity, blood pressure, renal hemodynamics and proteinuria in

hypertensive patients

▪ Mechanisms and treatment of allograft nephropathy

▪ Cardiovascular disease associated with chronic kidney disease


FACULTY POSITIONS


1983-1989 Assistant Professor of Medicine

University of Maryland School of Medicine

Baltimore, MD

1989-1994 Associate Professor of Medicine

University of Maryland School of Medicine

Baltimore, MD


1994-Present Professor of Medicine

University of Maryland School of Medicine

Baltimore, MD


1994-Present Director, Division of Nephrology

University of Maryland School of Medicine

Baltimore, MD


MAJOR ACADEMIC TASKS


1983-1990 Medical Director, Transplantation Service

University of Maryland Hospital

Baltimore, MD


1983-1990 Medical Director, Transplantation Clinic

University of Maryland Hospital

Baltimore, MD


1986-Present Task Force on Hypertensive Emergencies

University of Maryland Hospital

Baltimore, MD


1988-Present Medical Director, Clinical Research Unit

University of Maryland Hospital

Baltimore, MD


1990-1998 Director, Nephrology Fellowship Training Program

University of Maryland Hospital

Baltimore, MD


1991-Present Associate Director, Organ Transplantation Services

University of Maryland Hospital

Baltimore, MD


PROFESSIONAL MEMBERSHIPS


1980 Member, American College of Physicians

1982 Member, International Society of Nephrology

1983 Member, American Federation of Clinical Research

1984 Member, American Society of Nephrology

1984 Member, Baltimore City Medical Society

1984 Member, Medical & Chirurgical Faculty of Maryland

1985 Member, The Transplantation Society

1986 Member, American Society of Transplant Physicians

1986 Member, National Kidney Foundation

1986 Member, Renal Physicians Association

1987-88 Co-Director, Program Committee of the Third International

Interscience Conference on Hypertension in Blacks.

1988 Member, American Society of Hypertension

1988 Fellow, American College of Physicians

1988-91 Member, Scientific Review Committee, American Society of Transplant Physicians

1991-Present Reviewer of Abstracts for American Society of Transplantation Meeting

1992,1995,1997-present Reviewer of Abstracts for American Society of Nephrology

1993-1997 Member, Kidney-Pancreas Committee, American Society of Transplant Physicians

1993-1996 Member, Program Committee, American Society of Transplant Physicians

1993-1996 Member, Scientific Advisory Board, United Network of Organ Sharing (UNOS)

1994-1998 Member, American Society of Hypertension CME Committee

1994-1998 Member, Physicians Manpower and Training Committee,

American Society of Transplant Physicians

1998-present Member, Editorial Board of American Journal of Kidney Diseases

2004-present Journal of Clinical Hypertension, Hypertension, Transplantation, and many others

2004-2008 Associate Editor, American Journal of Kidney Diseases

2004-present Section Editor of Current Hypertension Reports and Current Opinion of Hypertension and Nephrology


HONORS, AWARDS


1974 Phi Beta Kappa

1982 National Kidney Foundation Fellowship Award

1984 Traveling Fellowship Award, IX International Congress of Nephrology

1986 Traveling Fellowship Award, XI International Congress of the Transplantation Society

1987 Traveling Fellowship Award, X International Congress of Nephrology

1991 Volunteer Service Award, National Kidney Foundation

1994 Alpha Omega Alpha

1998 Distinguished Research Award, International Society of Hypertension in Blacks


COMMITTEE AND SERVICE ACTIVITIES


1983-88 Member, Scientific Advisory Committee of Dr. John Warren's Program Project Entitled: "Complications of Long-Term Urinary Catheters in the Aged."

1983-84, 1986-present Housestaff Selection Committee

1984-1989 Department of Medicine Education Committee

1984-1986 Faculty Practice Offices Operations Committee

1984-1989 Task Force for Peer Review of Sophomore Pathology Medical School

1984,1985,1993 Judge, Medical School Research Day

1988-Present Student Appeals Committee

1985-1989 Clinical Years Curriculum Committee, Advisor for Senior Medical Students

1985-1989 Member, Baltimore Physicians for Social Responsibility

1986-present Chairman, Fund-Raising/Committee, National Kidney Foundation-Maryland

1986-present Department of Medicine Research Committee

1986-present Department of Medicine Benefits Committee

1987-present Board of Trustees, National Kidney Foundation - Maryland

1987-1990 Maryland Organ Procurement Center, Medical Advisory Board

1987-present Medical Advisory Board, National Kidney Foundation of Maryland

1987-present Reviewer of manuscripts for: Transplantation, American Journal of Kidney Diseases, Chest, New York State Journal of Medicine, American Journal of Hypertension, Journal of Human Hypertension, Life Sciences, Journal of the American Society of Nephrology, Archives of Internal Medicine, American Journal of Cardiology, Kidney International, Hypertension, New England Journal of Medicine, Journal of the American Medical association, and others

1987-present Editorial Board: transplantation, Hypertension, J Clinical Hypertension, Am J Nephrology, American Journal of Kidney Disease, and others

1988-1990 Board of Directors, Maryland Organ Procurement Center

1991-present Medical Advisory Board, Transplant Resource Center

1992- Member, Selection and Program Committee, Short-Term Research Training Program for Minority Undergraduate Students

1992- Preceptor, Short-Term Research Training Program for Minority Undergraduate Students

1993- Preceptor, Short-Term Research Training Program for Medical Students

Maryland State Advisory Council on HBP and Related Cardiovascular Risk Factors

1996-2002 Associate Editor, American Journal of Kidney Disease

1996-2000 Cardiorenal Study Section, NHLBI, National Institutes of Health

1997-present NIDDK Special Grants Review Committee, National Institutes of Health, R21, R33

2002-present Section Editor, Current Hypertension Reports

2003-present Section Editor, Current Opinion in Hypertension and Nephrology

2002-present NIDDK Grants Review Committee for Organ Transplantation

2007-present Grant Review Committee, VA Merit Review, Nephrology

2009- Section Editor, Clinical Nephrology


TEACHING ACTIVITIES


1983-present 4-6 months attending transplant service

1-2 months attending consultative service

1983-present 1-2 months attending medical service

1983-84, 1987-91 Sophomore physical diagnosis

1983-present Multiple didactic talks to medical housestaff, shock-trauma, second, third and fourth year medical students, pharmacology department, clinical chemistry department. Lecturer of sophomore medical school nephrology course.

1986-92 Preceptor, Medical Clerkship of third year Medical Students


RESEARCH GRANTS AND AWARDS

Peer Review Grants


1984 American Red Cross, $20,325. "Evaluation of HLA-typed apheresis byproducts as alloenhancing agents in prospective renal transplant recipients." Principal Investigator.

1984 Bressler Research Fund, $3,000. "Evaluation of HLA-typed apheresis byproducts as alloenhancing agents". Principal Investigator.

1985 American Red Cross, $20,325. "Evaluation of HLA-typed apheresis byproducts as alloenhancing in prospective renal transplant recipients." Principal Investigator.

1987 Designated Research Initiative Funds, State of Maryland, $8,500. "The role of calcium in lymphocyte activation and function." Principal Investigator.

1987 National Kidney Foundation of Maryland, $4,500. "Additive effects of calcium channel blockers and cyclosporine on lymphocyte function." Principal Investigator.

1988 National Kidney Foundation of Maryland, $2500. "Additive effects of calcium channel blockers and cyclosporine on lymphocyte activation and function. Principal Investigator

1989 National Kidney Foundation of Maryland, $2500. "Additive effects of calcium channel blockers, prostaglandin metabolites and cyclosporine on lymphocyte activation and function."

Principal Investigator.

1990 National Kidney Foundation of Maryland, $2500. "Additive effects of calcium channel blockers, prostaglandin metabolites and cyclosporine on lymphocyte activation and function."

Principal Investigator.

1991 National Kidney Foundation of Maryland, $2500. "Additive effects of calcium channel blockers, prostaglandin metabolites and cyclosporine on lymphocyte activation and function."

Principal Investigator.

1992 National Kidney Foundation of Maryland, $2500. "Effects of calcium channel blockers of potassium channel blockers on lymphocyte activation and function." Principal Investigator.

1994 American Heart Association Grant-In-Aid, $44,000. "Exercise, Insulin and Sodium in Black Hypertensives." Principal Investigator.

1994 SERCA Award, $418,652. "Insulin action, sodium and exercise in the hypertension of Aging."

Co-Investigator.

2001 NIDDK 1U01DK61022-01(NIH) – Appel (PI) $1,639,923 9/28/2001 – 8/31/2008

Johns Hopkins Medical Institutions, Chronic Renal Insufficiency Cohort Study, Site Co-Investigator

The main goal of this project is to identify risk for factors associated with accelerated loss of renal function in patients with chronic renal insufficiency and to identify risk factors for cardiovascular disease associated with this condition.

2002 NHLBI HL67031-01A(NIH) B. Howard (PI) $211,546 4/1/2002 – 3/31/2008

Medstar Research Institute, Stop Atherosclerosis in Natives Diabetes Study (SANDS). This project is an interventional trial with lower levels of blood pressure and LDL-cholesterol reduction in Native Americans with type II diabetes and microalbuminuria. Outcome is based on carotid intimal plaque thickening. Site Principal Investigator.

2002 NHLBI UO1HL72515(NIH) Shuldiner (PI) $197,547 9/30/2002 – 9/29/2006

University of Maryland School of Medicine, Genome-Wide Search for CVD Gene Environment Interaction. The major goal of this project is to identify genes that interact with the environment in shaping the risk of cardiovascular disease. Site Co-Investigator

2002 NIDDK UO1 DK61700-01(NIH) Bostom (PI) $140,000 2/12/2002 – 1/31/2007

Lifespan, Rhode Island Hospital, Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT), Site Principal Investigator.

2005 R01/DK066013 Kasiske (PI) $228,519 9/15/2005-5/31/2010

University of Minnesota, Live Unrelated Kidney Donor and Sibling Follow-up Study. To investigate

biomeasures of cardiovascular risk in kidney donors. Site Principal Investigator .

2007 NIDDK UO2 DK61700-06 (NIH) Bostom (PI) $535,175 2/1/2007 – 1/31/2012

Lifespan, Rhode Island Hospital, Folic Acid for Vascular Outcome Reduction in Transplantation (FAVORIT), Site Principal Investigator.

2007 No project number (Wilson) $50,000 7/1/2007-6/30/2008

University of Maryland Statewide Health Network Other Tobacco Related Diseases Research

The major goal of this project is to understand the effects of smoking on the graft function and explore the success of effectiveness of the smoking cessation in these patients with multiple co-morbidities. Role: PI

2008 NIDDK R21 AG033791 Mullins(PI) $200,00 11/2008-10-2010

Response to Medicare Reimbursement Policy Change by Minority and all ESRD Patients

Role: Co-investigator


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